FOXC2 and TAX1BP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FOXC2	TAX1BP1
Gene Name		forkhead box C2	Tax1 (human T-cell leukemia virus type I) binding protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytosol Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Chromatin DNA Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	Protein Binding Kinase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ossification Patterning Of Blood Vessels Metanephros Development Ureteric Bud Development Somitogenesis Lymphangiogenesis Blood Vessel Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Notch Signaling Pathway Mesoderm Development Heart Development Insulin Receptor Signaling Pathway Response To Hormone Positive Regulation Of Endothelial Cell Migration Neural Crest Cell Development Collagen Fibril Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Embryonic Heart Tube Development Positive Regulation Of Vascular Wound Healing Camera-type Eye Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Organ Growth Vascular Endothelial Growth Factor Receptor Signaling Pathway Paraxial Mesodermal Cell Fate Commitment Embryonic Viscerocranium Morphogenesis Artery Morphogenesis Regulation Of Blood Vessel Size Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Cell Proliferation Glomerular Endothelium Development Glomerular Visceral Epithelial Cell Differentiation Glomerular Mesangial Cell Development Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Apoptotic Process Involved In Outflow Tract Morphogenesis	Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process Innate Immune Response
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CNOT7 RBPMS TAX1BP1 TRIM27	40 interactors: ARHGAP1 CALCOCO2 CNTN2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN EMILIN1 FAM168A FAM189A2 FOXC2 GABARAP IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP1 TNIP3 TRAF6 TSG101 TSHZ3 UBC
Entrez ID		2303	8887
HPRD ID		03869	05618
Ensembl ID		ENSG00000176692	ENSG00000106052
Uniprot IDs		Q99958	A4D196 B4DSG5 Q86VP1
PDB IDs		1D5V
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Cytokine Production Regulation Of Gene Expression, Epigenetic Negative Regulation Of Calcium Ion Import Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Interferon-gamma Secretion Cytoplasmic MRNA Processing Body Assembly Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of SMAD Protein Import Into Nucleus Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Viral Release From Host Cell Regulation Of SMAD Protein Import Into Nucleus Regulation Of MRNA 3'-end Processing Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Interferon-gamma Production Negative Regulation Of Interleukin-2 Production RNA Processing Transcription, DNA-templated Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell RNA Biosynthetic Process Regulation Of Calcium Ion Import Regulation Of Protein Transport Nuclear-transcribed MRNA Poly(A) Tail Shortening Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Establishment Of Protein Localization RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Protein K63-linked Ubiquitination Cytokine Secretion Protein Trimerization Gene Silencing By MiRNA Negative Regulation Of Cytokine Secretion Negative Regulation Of Adaptive Immune Response Regulation Of Protein Localization Innate Immune Response Posttranscriptional Gene Silencing Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production	Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling MyD88-independent Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Organelle Disassembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleophagy Immune Response-regulating Signaling Pathway JNK Cascade Cellular Response To Stress Mitochondrion Degradation Regulation Of Vascular Wound Healing Regulation Of Type I Interferon Production Stress-activated MAPK Cascade Negative Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Autophagic Vacuole Assembly Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Macroautophagy Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Autophagy Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Protein Processing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Membrane Organization
Tagcloud ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Difference) ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Intersection) ?