FOXC2

Gene Name		forkhead box C2
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Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Chromatin DNA Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ossification Patterning Of Blood Vessels Metanephros Development Ureteric Bud Development Somitogenesis Lymphangiogenesis Blood Vessel Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Notch Signaling Pathway Mesoderm Development Heart Development Insulin Receptor Signaling Pathway Response To Hormone Positive Regulation Of Endothelial Cell Migration Neural Crest Cell Development Collagen Fibril Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Embryonic Heart Tube Development Positive Regulation Of Vascular Wound Healing Camera-type Eye Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Organ Growth Vascular Endothelial Growth Factor Receptor Signaling Pathway Paraxial Mesodermal Cell Fate Commitment Embryonic Viscerocranium Morphogenesis Artery Morphogenesis Regulation Of Blood Vessel Size Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Cell Proliferation Glomerular Endothelium Development Glomerular Visceral Epithelial Cell Differentiation Glomerular Mesangial Cell Development Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Apoptotic Process Involved In Outflow Tract Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CNOT7 RBPMS TAX1BP1 TRIM27
Entrez ID		2303
HPRD ID		03869
Ensembl ID		ENSG00000176692
Uniprot IDs		Q99958
PDB IDs		1D5V
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Cytokine Production Regulation Of Gene Expression, Epigenetic Negative Regulation Of Calcium Ion Import Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Interferon-gamma Secretion Cytoplasmic MRNA Processing Body Assembly Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of SMAD Protein Import Into Nucleus Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Viral Release From Host Cell Regulation Of SMAD Protein Import Into Nucleus Regulation Of MRNA 3'-end Processing Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Interferon-gamma Production Negative Regulation Of Interleukin-2 Production RNA Processing Transcription, DNA-templated Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell RNA Biosynthetic Process Regulation Of Calcium Ion Import Regulation Of Protein Transport Nuclear-transcribed MRNA Poly(A) Tail Shortening Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Establishment Of Protein Localization RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Protein K63-linked Ubiquitination Cytokine Secretion Protein Trimerization Gene Silencing By MiRNA Negative Regulation Of Cytokine Secretion Negative Regulation Of Adaptive Immune Response Regulation Of Protein Localization Innate Immune Response Posttranscriptional Gene Silencing Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production
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