SYT17 and SNRNP35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYT17	SNRNP35
Description		synaptotagmin 17	small nuclear ribonucleoprotein U11/U12 subunit 35
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GO Annotations	Cellular Component	Trans-Golgi Network Plasma Membrane Membrane Exocytic Vesicle Postsynapse Glutamatergic Synapse	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus Ribonucleoprotein Complex
	Molecular Function	SNARE Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium Ion Sensor Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding SnRNA Binding
	Biological Process	Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Cell Differentiation Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Positive Regulation Of Dendrite Extension	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Alcohol dependence ( 21876473) Appendicular lean mass ( 33097823) Fruit consumption ( 32066663) Parkinson's disease ( 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Educational attainment ( 25201988) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		49 interacting genes: AK8 APP APTX BLZF1 CBY2 CCDC102B CCDC33 CCDC85B CCNB1IP1 CEP63 CEP70 CHMP4A COG6 DEPDC5 EXOC8 FAM9B FRMD6 GMCL1 GOLGA2 GOLGA6A HIP1 HOOK2 IKZF1 LSM7 LZTS1 LZTS2 MAD1L1 MAJIN MCC MEOX1 MEOX2 NIF3L1 NINL PFDN5 PIBF1 PICK1 POF1B RUNDC3A SDCBP2 SNRNP35 SSX2IP TRAF2 TRIM27 TSC22D4 TSNAX VPS9D1 ZNF438 ZNF597 ZRANB1	16 interacting genes: - ANKRD11 APP CCDC57 CKS1B CLK3 ILK MAP4K2 PLEKHF2 SBK3 SNAPC3 SRPK2 SYT17 TAB1 TNFSF11 U2AF1
Entrez ID		51760	11066
HPRD ID		17425	15595
Ensembl ID		ENSG00000103528	ENSG00000184209
Uniprot IDs		H3BN78 H3BQZ6 H3BRH9 Q9BSW7	Q16560
PDB IDs		2ENP	8R7N 8Y6O 9GBW 9GBZ 9GCM
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Identical Protein Binding Cytoskeleton Somite Specification Centrosome	Intracellular Signaling Cassette Positive Regulation Of JNK Cascade Protein Serine/threonine Kinase Activity Protein Kinase Activity Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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