FHIT and HSPD1

  • Number of citations of the paper that reports this interaction (PubMedID 19004824)
  • 22
  • Data Source:
  • HPRD (in vitro)

FHIT

HSPD1

Description fragile histidine triad diadenosine triphosphatase heat shock protein family D (Hsp60) member 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Adverse response to lamotrigine and phenytoin ( 22379998)
  • Age at first sexual intercourse ( 34211149)
  • Aortic root size ( 21223598)
  • Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598)
  • Asperger disorder ( 21182207)
  • Attention deficit hyperactivity disorder ( 18821565)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood pressure ( 24954895)
  • Blood protein levels ( 30072576)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index ( 28892062 28552196 28448500 26961502 25673413)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Body mass index in physically active individuals ( 28448500)
  • Body size at age 10 ( 32376654)
  • Broad depression or schizophrenia ( 30626913)
  • Bronchopulmonary dysplasia ( 23897914)
  • Caudal anterior-cingulate cortex volume ( 31530798)
  • Cognitive function ( 25644384)
  • Conotruncal heart defects ( 24800985)
  • Depressive symptom measurement or major depressive disorder ( 28049566)
  • Differentiated thyroid cancer ( 28703219)
  • Falling risk ( 32999390)
  • Femur bone mineral density x serum urate levels interaction ( 34046847)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Hip circumference ( 28552196)
  • Intracranial aneurysm ( 29531279)
  • Iris color (L* coordinate) ( 30895295)
  • Irritable bowel syndrome ( 29673008)
  • L1-L4 bone mineral density x serum urate levels interaction ( 34046847)
  • Lung function (maximal voluntary ventilation) ( 29095316)
  • Major coronary event in cardiovascular disease (time to event) (darapladib treatment interaction) ( 28753643)
  • Major coronary event in placebo-treated cardiovascular disease (time to event) ( 28753643)
  • Major depressive disorder ( 20125088)
  • Methadone dose in opioid dependence ( 28115739)
  • Myopia (pathological) ( 23049088)
  • Orofacial clefts ( 22419666)
  • Papillary thyroid cancer ( 28703219)
  • Pars triangularis volume ( 31530798)
  • Photic sneeze reflex ( 27182965)
  • Postoperative myocardial infarction after cardiac surgery ( 30678657)
  • Refractive error ( 32231278)
  • Response to amphetamines ( 22952603)
  • Response to citalopram treatment ( 22760553)
  • Schizophrenia ( 30285260)
  • Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
  • Urinary metabolite levels in chronic kidney disease ( 29545352)
  • Waist circumference ( 28552196)
  • Weight ( 28552196)
Interacting Genes 13 interacting genes: BCAS2 CTNNB1 DDIT4L FDXR GSN HSPD1 PRPF6 RAB40B REL SRC TRIM23 UBE2I YTHDF1 58 interacting genes: ALDH2 APP BAK1 BRCA1 CA2 CASP3 CASP9 CEP70 CFTR CLEC7A CLU CYSRT1 DHFR DUX4 ERBB2 ERG FAM107A FHIT FNDC3B H2BC21 HSPE1 ITGA3 ITGB1 KRT31 KRT34 KRT40 KRTAP10-3 KRTAP10-8 KRTAP5-9 LINC01554 LRRK2 LZTS2 MAPK6 MCPH1 NOS1AP NOTCH2NLA NR3C1 OGT PDE4B PLCG2 PLG PPP2R1A PPP2R1B PRKACA PRNP PTEN PTPN11 RASA1 RGS20 SAMD3 SUMO2 SUMO4 SUPT6H TLR1 TMCC2 TRIM63 UBASH3A YWHAG
Entrez ID 2272 3329
HPRD ID 03096 00318
Ensembl ID ENSG00000189283 ENSG00000144381
Uniprot IDs P49789 A0A024R3X4 P10809
PDB IDs 1FHI 1FIT 2FHI 2FIT 3FIT 4FIT 5FIT 6FIT 7P8P 4PJ1 6HT7 6MRC 6MRD 7AZP 7L7S 8G7J 8G7K 8G7L 8G7M 8G7N 8G7O 8U39
Enriched GO Terms of Interacting Partners?
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