MAPK15 and GABARAP

Number of citations of the paper that reports this interaction (PMID 22948227)
9

Data Source:
BioGRID (pull down, affinity chromatography technology)

		MAPK15	GABARAP
Gene Name		mitogen-activated protein kinase 15	GABA(A) receptor-associated protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Intracellular Nucleus	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Lysosome Autophagic Vacuole Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Extrinsic Component Of Membrane Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	MAP Kinase Activity ATP Binding SH3 Domain Binding	Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter MAPK Cascade Positive Regulation Of Protein Phosphorylation Negative Regulation Of DNA Replication Positive Regulation Of Protein Ubiquitination Response To Estradiol Positive Regulation Of Protein Catabolic Process Protein Autophosphorylation	Autophagic Vacuole Assembly Microtubule Cytoskeleton Organization Mitochondrion Degradation Protein Targeting Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleophagy Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: CLIC3 CSK GABARAP GABARAPL1 MBP NR3C1 SRC TGFB1I1	29 interactors: AES ATG101 ATG13 ATG3 ATG4B ATG7 DMPK DVL2 GABRG1 GABRG2 GABRG3 GPHN HDAC5 MAPK15 MLH1 MPC1 NSF PGS1 PKP4 RB1CC1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TUBB3 ULK1 ULK2 VPS28
Entrez ID		225689	11337
HPRD ID		16867	05496
Ensembl ID		ENSG00000181085
Uniprot IDs		Q8TD08	O95166 Q6IAW1
PDB IDs			1GNU 1KLV 1KM7 1KOT 3D32 3DOW
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Cell Communication Morphogenesis Of An Epithelium Nucleophagy Intracellular Receptor Signaling Pathway Tissue Morphogenesis Mitochondrion Degradation Regulation Of Bone Resorption Organelle Disassembly Peptidyl-tyrosine Autophosphorylation Regulation Of Bone Remodeling Autophagic Vacuole Assembly Membrane Organization Response To Progesterone Response To Hormone Macroautophagy Mammary Gland Duct Morphogenesis Response To Stress Regulation Of Tissue Remodeling Response To Stimulus Response To Fatty Acid Epithelium Development Negative Regulation Of Signal Transduction Signaling T Cell Costimulation Response To Nutrient Levels Mammary Gland Morphogenesis Glucocorticoid Mediated Signaling Pathway Adherens Junction Organization Negative Regulation Of Signaling Response To Extracellular Stimulus Response To Steroid Hormone Mammary Gland Epithelium Development Regulation Of Glucose Metabolic Process Vacuole Organization Regulation Of Cytokine Production Cellular Response To Progesterone Stimulus Cellular Response To Hormone Stimulus Cellular Response To Stimulus Membrane Fusion Cellular Response To Starvation Defense Response To Nematode Negative Regulation Of Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Carbohydrate Metabolic Process Gland Morphogenesis Autophagy Epidermal Growth Factor Receptor Signaling Pathway Response To Corticosteroid ERBB Signaling Pathway	Autophagic Vacuole Assembly Autophagy Macroautophagy Cellular Response To Extracellular Stimulus Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Vacuole Organization Response To Extracellular Stimulus Response To Nutrient Levels Organelle Assembly Regulation Of Autophagy Cell Communication Cellular Component Assembly Nucleophagy Catabolic Process Organelle Organization Mitochondrion Degradation Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Of Autophagy Organelle Disassembly Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Response To Stimulus Response To External Stimulus Cellular Response To Stress Membrane Organization Response To Stress Positive Regulation Of Macroautophagy Cellular Process Cellular Response To Nitrogen Starvation Cellular Metabolic Process Protein Localization Positive Regulation Of Viral Genome Replication Chloride Transmembrane Transport Nucleus Organization C-terminal Protein Lipidation Chloride Transport Regulation Of Cell Size Regulation Of Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Signaling Protein Localization To Membrane Axon Extension Positive Regulation Of Metabolic Process Anion Transmembrane Transport Glycine Receptor Clustering Nuclear Speck Organization Regulation Of Autophagic Vacuole Maturation
Tagcloud ?		atypical autonomous autonomously biogenesis consequently coordinates delay dilp dilps drosophila effector epistatically erk7 erk8 humoral impede ipcs larval limiting neurosecretory nutrient nutrition operates ribosome secreting secretion starvation surveillance uncover	akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?		atypical autonomous autonomously biogenesis consequently coordinates delay dilp dilps drosophila effector epistatically erk7 erk8 humoral impede ipcs larval limiting neurosecretory nutrient nutrition operates ribosome secreting secretion starvation surveillance uncover	akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?