GABARAP and TBC1D25

Number of citations of the paper that reports this interaction (PMID 21383079)
26

Data Source:
BioGRID (two hybrid, pull down)

		GABARAP	TBC1D25
Gene Name		GABA(A) receptor-associated protein	TBC1 domain family, member 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Lysosome Autophagic Vacuole Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Extrinsic Component Of Membrane Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm	Autophagic Vacuole Cytoplasmic Vesicle
	Molecular Function	Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding	Rab GTPase Activator Activity Protein Binding
	Biological Process	Autophagic Vacuole Assembly Microtubule Cytoskeleton Organization Mitochondrion Degradation Protein Targeting Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleophagy Membrane Fusion	Autophagy Positive Regulation Of Rab GTPase Activity Regulation Of Autophagic Vacuole Maturation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: AES ATG101 ATG13 ATG3 ATG4B ATG7 DMPK DVL2 GABRG1 GABRG2 GABRG3 GPHN HDAC5 MAPK15 MLH1 MPC1 NSF PGS1 PKP4 RB1CC1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TUBB3 ULK1 ULK2 VPS28	8 interactors: FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B RAB2A
Entrez ID		11337	4943
HPRD ID		05496	08948
Ensembl ID			ENSG00000068354
Uniprot IDs		O95166 Q6IAW1	Q3MII6
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW
Enriched GO Terms of Interacting Partners?		Autophagic Vacuole Assembly Autophagy Macroautophagy Cellular Response To Extracellular Stimulus Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Vacuole Organization Response To Extracellular Stimulus Response To Nutrient Levels Organelle Assembly Regulation Of Autophagy Cell Communication Cellular Component Assembly Nucleophagy Catabolic Process Organelle Organization Mitochondrion Degradation Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Of Autophagy Organelle Disassembly Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Response To Stimulus Response To External Stimulus Cellular Response To Stress Membrane Organization Response To Stress Positive Regulation Of Macroautophagy Cellular Process Cellular Response To Nitrogen Starvation Cellular Metabolic Process Protein Localization Positive Regulation Of Viral Genome Replication Chloride Transmembrane Transport Nucleus Organization C-terminal Protein Lipidation Chloride Transport Regulation Of Cell Size Regulation Of Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Signaling Protein Localization To Membrane Axon Extension Positive Regulation Of Metabolic Process Anion Transmembrane Transport Glycine Receptor Clustering Nuclear Speck Organization Regulation Of Autophagic Vacuole Maturation	Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Membrane Fusion Cellular Response To Starvation Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Cellular Response To Nitrogen Starvation Mitochondrion Organization Response To Nutrient Levels Response To External Stimulus Response To Extracellular Stimulus Organelle Assembly Membrane Organization Cellular Response To Stimulus Cellular Response To Stress Catabolic Process Organelle Organization Cellular Component Assembly Response To Stimulus Cell Communication Response To Stress Establishment Of Localization In Cell Negative Regulation Of Macroautophagy Cellular Localization Establishment Of Mitochondrion Localization Axon Guidance Protein Transport Establishment Of Protein Localization Positive Regulation Of ATPase Activity Negative Regulation Of Autophagy Intracellular Transport Mitochondrion Localization Axonogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of ATPase Activity Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?