GABARAP and GABRG2

Number of citations of the paper that reports this interaction (PMID 9892355)
76

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		GABARAP	GABRG2
Gene Name		GABA(A) receptor-associated protein	gamma-aminobutyric acid (GABA) A receptor, gamma 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Lysosome Autophagic Vacuole Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Extrinsic Component Of Membrane Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Axon Dendrite Membrane Chloride Channel Complex Postsynaptic Membrane Inhibitory Synapse GABA-A Receptor Complex
	Molecular Function	Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Protein Binding Benzodiazepine Receptor Activity
	Biological Process	Autophagic Vacuole Assembly Microtubule Cytoskeleton Organization Mitochondrion Degradation Protein Targeting Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleophagy Membrane Fusion	Transport Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Post-embryonic Development Adult Behavior Ion Transmembrane Transport Synaptic Transmission, GABAergic Transmembrane Transport Cellular Response To Histamine Chloride Transmembrane Transport
Pathways			GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: AES ATG101 ATG13 ATG3 ATG4B ATG7 DMPK DVL2 GABRG1 GABRG2 GABRG3 GPHN HDAC5 MAPK15 MLH1 MPC1 NSF PGS1 PKP4 RB1CC1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TUBB3 ULK1 ULK2 VPS28	6 interactors: DRD5 GABARAP PPP3CA PRKCA PRKCB ZDHHC3
Entrez ID		11337	2566
HPRD ID		05496	00663
Ensembl ID			ENSG00000113327
Uniprot IDs		O95166 Q6IAW1	P18507
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW
Enriched GO Terms of Interacting Partners?		Autophagic Vacuole Assembly Autophagy Macroautophagy Cellular Response To Extracellular Stimulus Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Vacuole Organization Response To Extracellular Stimulus Response To Nutrient Levels Organelle Assembly Regulation Of Autophagy Cell Communication Cellular Component Assembly Nucleophagy Catabolic Process Organelle Organization Mitochondrion Degradation Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Of Autophagy Organelle Disassembly Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Response To Stimulus Response To External Stimulus Cellular Response To Stress Membrane Organization Response To Stress Positive Regulation Of Macroautophagy Cellular Process Cellular Response To Nitrogen Starvation Cellular Metabolic Process Protein Localization Positive Regulation Of Viral Genome Replication Chloride Transmembrane Transport Nucleus Organization C-terminal Protein Lipidation Chloride Transport Regulation Of Cell Size Regulation Of Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Signaling Protein Localization To Membrane Axon Extension Positive Regulation Of Metabolic Process Anion Transmembrane Transport Glycine Receptor Clustering Nuclear Speck Organization Regulation Of Autophagic Vacuole Maturation	Histone H3-T6 Phosphorylation Synaptic Transmission Cell-cell Signaling Cellular Response To Carbohydrate Stimulus Cellular Chemical Homeostasis Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glucose Transport Response To Carbohydrate Cellular Homeostasis Regulation Of Cardiac Muscle Hypertrophy Activation Of Adenylate Cyclase Activity Chemical Homeostasis Response To Amphetamine Mitotic Nuclear Envelope Disassembly Positive Regulation Of Adenylate Cyclase Activity Cellular Calcium Ion Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway Calcium Ion Homeostasis Histone Phosphorylation Nuclear Envelope Disassembly Positive Regulation Of Lyase Activity Peptidyl-threonine Phosphorylation Response To Amine Regulation Of Adenylate Cyclase Activity Negative Regulation Of Signaling Negative Regulation Of Transport Cellular Metal Ion Homeostasis Positive Regulation Of CAMP Biosynthetic Process Protein Targeting Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cyclase Activity Nuclear Envelope Organization Positive Regulation Of CAMP Metabolic Process Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Homeostatic Process Protein Transport Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Cyclic Nucleotide Metabolic Process Establishment Of Protein Localization Regulation Of CAMP Biosynthetic Process Cell Surface Receptor Signaling Pathway Ion Homeostasis Regulation Of Glucose Transport Transition Between Fast And Slow Fiber Positive Regulation Of Dense Core Granule Biogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of CAMP Metabolic Process Wound Healing
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	agonistic alpha6 aminobutyric antiepileptic beta3 compromise dravet dysfunctions epilepsy gabaa gabra1 gabra6 gabrb3 gabrd gamma2 gastaut gated gating hyperpolarization infantile insufficiencies lennox myoclonic nonsense pathomechanisms pentamers seizures spasms
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	agonistic alpha6 aminobutyric antiepileptic beta3 compromise dravet dysfunctions epilepsy gabaa gabra1 gabra6 gabrb3 gabrd gamma2 gastaut gated gating hyperpolarization infantile insufficiencies lennox myoclonic nonsense pathomechanisms pentamers seizures spasms
Tagcloud (Intersection) ?