GABARAP and TFRC

Number of citations of the paper that reports this interaction (PMID 11997026)
7

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		GABARAP	TFRC
Gene Name		GABA(A) receptor-associated protein	transferrin receptor
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Lysosome Autophagic Vacuole Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Extrinsic Component Of Membrane Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Endosome Plasma Membrane Integral Component Of Plasma Membrane Coated Pit External Side Of Plasma Membrane Cell Surface Membrane Cytoplasmic Membrane-bounded Vesicle Vesicle Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding	Double-stranded RNA Binding Transferrin Receptor Activity Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Autophagic Vacuole Assembly Microtubule Cytoskeleton Organization Mitochondrion Degradation Protein Targeting Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleophagy Membrane Fusion	Regulation Of Cell Growth Cellular Iron Ion Homeostasis Receptor-mediated Endocytosis Viral Process Osteoclast Differentiation Transferrin Transport Cellular Response To Drug Regulation Of Cell Proliferation Positive Regulation Of Bone Resorption Transmembrane Transport Iron Ion Import
Pathways			Iron uptake and transport Golgi Associated Vesicle Biogenesis Transferrin endocytosis and recycling trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 20139978 19862010) Pancreatic cancer ( 22158540) Red blood cell traits ( 23222517)
Protein-Protein Interactions		29 interactors: AES ATG101 ATG13 ATG3 ATG4B ATG7 DMPK DVL2 GABRG1 GABRG2 GABRG3 GPHN HDAC5 MAPK15 MLH1 MPC1 NSF PGS1 PKP4 RB1CC1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TUBB3 ULK1 ULK2 VPS28	11 interactors: ACAP1 B4GALT1 CD247 CD4 GABARAP HFE RAB5B RAB8A RANBP9 SGTA TF
Entrez ID		11337	7037
HPRD ID		05496	01812
Ensembl ID			ENSG00000072274
Uniprot IDs		O95166 Q6IAW1	A8K6Q8 P02786
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW	1CX8 1DE4 1SUV 2NSU 3KAS 3S9L 3S9M 3S9N
Enriched GO Terms of Interacting Partners?		Autophagic Vacuole Assembly Autophagy Macroautophagy Cellular Response To Extracellular Stimulus Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Vacuole Organization Response To Extracellular Stimulus Response To Nutrient Levels Organelle Assembly Regulation Of Autophagy Cell Communication Cellular Component Assembly Nucleophagy Catabolic Process Organelle Organization Mitochondrion Degradation Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Of Autophagy Organelle Disassembly Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Response To Stimulus Response To External Stimulus Cellular Response To Stress Membrane Organization Response To Stress Positive Regulation Of Macroautophagy Cellular Process Cellular Response To Nitrogen Starvation Cellular Metabolic Process Protein Localization Positive Regulation Of Viral Genome Replication Chloride Transmembrane Transport Nucleus Organization C-terminal Protein Lipidation Chloride Transport Regulation Of Cell Size Regulation Of Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Signaling Protein Localization To Membrane Axon Extension Positive Regulation Of Metabolic Process Anion Transmembrane Transport Glycine Receptor Clustering Nuclear Speck Organization Regulation Of Autophagic Vacuole Maturation	Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Defense Response To Virus By Virus Cellular Protein Localization Cellular Localization Transport Rab Protein Signal Transduction Cellular Response To Iron Ion Starvation Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation T Cell Costimulation Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Iron Ion Transport Regulation Of Defense Response To Virus Cellular Iron Ion Homeostasis T Cell Receptor Signaling Pathway Establishment Of Localization In Cell Iron Ion Homeostasis Lactose Biosynthetic Process Golgi Vesicle Fusion To Target Membrane Membrane Fusion Viral Process Immune System Process Response To Stimulus Antigen Receptor-mediated Signaling Pathway Cellular Response To Starvation Transition Metal Ion Homeostasis Response To Stress Regulation Of Exocytosis Disaccharide Metabolic Process Positive Regulation Of Immune Response Cellular Response To Nutrient Levels Response To Starvation Iron Ion Import Into Cell Vesicle-mediated Transport Penetration Of Zona Pellucida Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Plasma Membrane To Endosome Transport Intracellular Transport Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of T Cell Activation Cellular Response To Extracellular Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Ras Protein Signal Transduction Multicellular Organismal Homeostasis Regulation Of Acrosome Reaction Positive Regulation Of Cell-cell Adhesion Cell Communication
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman top2a tubb3 tyms vegfr2
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman top2a tubb3 tyms vegfr2
Tagcloud (Intersection) ?