GABARAP and GABRG3

Number of citations of the paper that reports this interaction (PMID 11948245)
11

Data Source:
HPRD (in vitro, in vivo)

		GABARAP	GABRG3
Gene Name		GABA(A) receptor-associated protein	gamma-aminobutyric acid (GABA) A receptor, gamma 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Lysosome Autophagic Vacuole Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Extrinsic Component Of Membrane Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm	Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane
	Molecular Function	Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity
	Biological Process	Autophagic Vacuole Assembly Microtubule Cytoskeleton Organization Mitochondrion Degradation Protein Targeting Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleophagy Membrane Fusion	Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Ion Transmembrane Transport Response To Drug Transmembrane Transport Chloride Transmembrane Transport
Pathways			GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033) Corneal curvature ( 22969067)
Protein-Protein Interactions		29 interactors: AES ATG101 ATG13 ATG3 ATG4B ATG7 DMPK DVL2 GABRG1 GABRG2 GABRG3 GPHN HDAC5 MAPK15 MLH1 MPC1 NSF PGS1 PKP4 RB1CC1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TUBB3 ULK1 ULK2 VPS28	1 interactors: GABARAP
Entrez ID		11337	2567
HPRD ID		05496	02579
Ensembl ID			ENSG00000182256
Uniprot IDs		O95166 Q6IAW1	Q99928
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW
Enriched GO Terms of Interacting Partners?		Autophagic Vacuole Assembly Autophagy Macroautophagy Cellular Response To Extracellular Stimulus Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Vacuole Organization Response To Extracellular Stimulus Response To Nutrient Levels Organelle Assembly Regulation Of Autophagy Cell Communication Cellular Component Assembly Nucleophagy Catabolic Process Organelle Organization Mitochondrion Degradation Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Of Autophagy Organelle Disassembly Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Response To Stimulus Response To External Stimulus Cellular Response To Stress Membrane Organization Response To Stress Positive Regulation Of Macroautophagy Cellular Process Cellular Response To Nitrogen Starvation Cellular Metabolic Process Protein Localization Positive Regulation Of Viral Genome Replication Chloride Transmembrane Transport Nucleus Organization C-terminal Protein Lipidation Chloride Transport Regulation Of Cell Size Regulation Of Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Signaling Protein Localization To Membrane Axon Extension Positive Regulation Of Metabolic Process Anion Transmembrane Transport Glycine Receptor Clustering Nuclear Speck Organization Regulation Of Autophagic Vacuole Maturation	Nucleophagy Mitochondrion Degradation Organelle Disassembly Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Extrinsic Apoptotic Signaling Pathway Membrane Fusion Cellular Response To Starvation Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	15q26 angelman bisulfite chromosomes conferring disomy dmrs imprinted imprinting intergenic lies loci magel2 marks maternal methylated oligonucleotide parent paternal prader profiled psychosis snrpn tiling uniparental upd upd15 validating willi
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	15q26 angelman bisulfite chromosomes conferring disomy dmrs imprinted imprinting intergenic lies loci magel2 marks maternal methylated oligonucleotide parent paternal prader profiled psychosis snrpn tiling uniparental upd upd15 validating willi
Tagcloud (Intersection) ?