Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
FCER1G and PLCG2
Number of citations of the paper that reports this interaction (PMID
10469124
)
9
Data Source:
HPRD
(in vivo)
FCER1G
PLCG2
Gene Name
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
phospholipase C, gamma 2 (phosphatidylinositol-specific)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Cytosol
Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
Phosphatidylinositol Phospholipase C Activity
Phospholipase C Activity
Signal Transducer Activity
Protein Binding
Biological Process
Positive Regulation Of Type IIa Hypersensitivity
Positive Regulation Of Type III Hypersensitivity
Positive Regulation Of Type I Hypersensitivity
Neutrophil Activation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Serotonin Secretion By Platelet
Phagocytosis, Engulfment
Integrin-mediated Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Mast Cell Cytokine Production
Negative Regulation Of Mast Cell Apoptotic Process
Fc-epsilon Receptor Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Positive Regulation Of Mast Cell Degranulation
Innate Immune Response
Mast Cell Activation
Positive Regulation Of Phagocytosis
Leukocyte Migration
Protein Localization To Plasma Membrane
Follicular B Cell Differentiation
Phosphatidylinositol Biosynthetic Process
Blood Coagulation
Phospholipid Catabolic Process
Regulation Of Gene Expression
Wnt Signaling Pathway
Calcium-mediated Signaling
Platelet Activation
B Cell Differentiation
Activation Of Store-operated Calcium Channel Activity
Response To Lipopolysaccharide
Inositol Trisphosphate Biosynthetic Process
Fc-epsilon Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Negative Regulation Of Programmed Cell Death
Inositol Phosphate Metabolic Process
Small Molecule Metabolic Process
Innate Immune Response
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Release Of Sequestered Calcium Ion Into Cytosol
Pathways
Platelet Adhesion to exposed collagen
FCERI mediated NF-kB activation
GPVI-mediated activation cascade
Fc epsilon receptor (FCERI) signaling
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
Platelet activation, signaling and aggregation
Role of LAT2/NTAL/LAB on calcium mobilization
Cell surface interactions at the vascular wall
Innate Immune System
Signaling by the B Cell Receptor (BCR)
DAP12 interactions
FCERI mediated MAPK activation
Inositol phosphate metabolism
DAP12 signaling
Toll-Like Receptors Cascades
Synthesis of IP3 and IP4 in the cytosol
Toll Like Receptor 4 (TLR4) Cascade
Role of phospholipids in phagocytosis
GPVI-mediated activation cascade
Fc epsilon receptor (FCERI) signaling
FCERI mediated Ca+2 mobilization
Fcgamma receptor (FCGR) dependent phagocytosis
Platelet activation, signaling and aggregation
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Adaptive Immune System
Innate Immune System
Drugs
Benzylpenicilloyl Polylysine
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
FCER1A
FCGR3A
GP6
KIR2DL4
LYN
NCR1
PLCG2
SYK
34 interactors:
BLK
BLNK
BTK
CBLB
CD19
DAPP1
EGFR
EPOR
ERBB2
FCER1G
FLT1
FYN
GAB1
GAB2
HCK
IRS1
ITK
JAK1
JAK2
KDR
KHDRBS1
LAT
LAT2
LCK
LCP2
LIME1
LYN
NPM1
PRKD1
SH3BP2
SHC1
SYK
TEC
ZNF512B
Entrez ID
2207
5336
HPRD ID
00916
02570
Ensembl ID
ENSG00000158869
ENSG00000197943
Uniprot IDs
P30273
P16885
PDB IDs
2K2J
2W2W
2W2X
Enriched GO Terms of Interacting Partners
?
Regulation Of Immune Response
Fc Receptor Signaling Pathway
Regulation Of Immune System Process
Defense Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Mast Cell Degranulation
Positive Regulation Of Interleukin-3 Biosynthetic Process
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Regulation Of Mast Cell Activation
B Cell Receptor Signaling Pathway
Regulation Of Regulated Secretory Pathway
Response To Stress
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process
Platelet Activation
Immune System Process
Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Immune Response
Serotonin Secretion
Phagocytosis
Cell Activation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Ammonium Transport
Serotonin Transport
Innate Immune Response
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Positive Regulation Of Immune System Process
Signal Transduction
Blood Coagulation
Hemostasis
Positive Regulation Of Mast Cell Degranulation
Positive Regulation Of Mast Cell Activation
Antigen Receptor-mediated Signaling Pathway
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Signaling
Leukocyte Activation
Regulation Of Platelet Aggregation
Cell Communication
Regulation Of Exocytosis
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Regulated Secretory Pathway
Regulation Of Body Fluid Levels
Immune Response
Leukotriene Biosynthetic Process
Wound Healing
Monoamine Transport
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Innate Immune Response
Peptidyl-tyrosine Autophosphorylation
Regulation Of Immune Response
Enzyme Linked Receptor Protein Signaling Pathway
Immune Response
Protein Autophosphorylation
Immune System Process
Regulation Of Immune System Process
Peptidyl-tyrosine Phosphorylation
Defense Response
Cell Surface Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Signal Transduction
Immune Response-activating Cell Surface Receptor Signaling Pathway
Signaling
Cell Communication
B Cell Receptor Signaling Pathway
Intracellular Signal Transduction
Cellular Response To Stimulus
Regulation Of Cell Proliferation
Positive Regulation Of Immune Response
Positive Regulation Of Immune System Process
Peptidyl-amino Acid Modification
Cell Activation
Positive Regulation Of Signal Transduction
Response To Stimulus
Response To Stress
Leukocyte Activation
Protein Phosphorylation
Cellular Response To Organic Substance
Response To Organic Substance
Regulation Of Cell Activation
Cell Migration
Locomotion
Phosphorylation
Cell Motility
Mast Cell Activation
Phosphatidylinositol-mediated Signaling
Wound Healing
Leukocyte Migration
Movement Of Cell Or Subcellular Component
Regulation Of Signaling
Regulation Of Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Tagcloud
?
16x10
associations
chrne
comprehensively
dysregulated
escc
esccs
esophageal
fyn
gc
gcs
germline
gnai3
han
itch
map2k1
map2k4
mapk8
observe
pak4
pik3r3
prlr
rank
resampling
rps6kb2
tln1
validate
warranted
wasl
Tagcloud (Difference)
?
16x10
associations
chrne
comprehensively
dysregulated
escc
esccs
esophageal
fyn
gc
gcs
germline
gnai3
han
itch
map2k1
map2k4
mapk8
observe
pak4
pik3r3
prlr
rank
resampling
rps6kb2
tln1
validate
warranted
wasl
Tagcloud (Intersection)
?