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FCER1G and FCGR3A
Number of citations of the paper that reports this interaction (PMID
15778339
)
27
Data Source:
HPRD
(in vivo)
FCER1G
FCGR3A
Gene Name
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
IgG Binding
Biological Process
Positive Regulation Of Type IIa Hypersensitivity
Positive Regulation Of Type III Hypersensitivity
Positive Regulation Of Type I Hypersensitivity
Neutrophil Activation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Serotonin Secretion By Platelet
Phagocytosis, Engulfment
Integrin-mediated Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Mast Cell Cytokine Production
Negative Regulation Of Mast Cell Apoptotic Process
Fc-epsilon Receptor Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Positive Regulation Of Mast Cell Degranulation
Innate Immune Response
Mast Cell Activation
Positive Regulation Of Phagocytosis
Leukocyte Migration
Protein Localization To Plasma Membrane
Immune Response
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Regulation Of Immune Response
Pathways
Platelet Adhesion to exposed collagen
FCERI mediated NF-kB activation
GPVI-mediated activation cascade
Fc epsilon receptor (FCERI) signaling
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
Platelet activation, signaling and aggregation
Role of LAT2/NTAL/LAB on calcium mobilization
Cell surface interactions at the vascular wall
Innate Immune System
Role of phospholipids in phagocytosis
Fcgamma receptor (FCGR) dependent phagocytosis
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
FCGR activation
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Adaptive Immune System
Drugs
Benzylpenicilloyl Polylysine
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
8 interactors:
FCER1A
FCGR3A
GP6
KIR2DL4
LYN
NCR1
PLCG2
SYK
15 interactors:
APCS
APP
CD247
CD38
CD4
FCER1G
FCGR1A
GP6
IGHG1
LCK
PTPRC
SHC1
SYK
ZAP70
ZBTB25
Entrez ID
2207
2214
HPRD ID
00916
00903
Ensembl ID
ENSG00000158869
ENSG00000203747
Uniprot IDs
P30273
E9PG94
M9MML0
P08637
PDB IDs
3AY4
3SGJ
3SGK
Enriched GO Terms of Interacting Partners
?
Regulation Of Immune Response
Fc Receptor Signaling Pathway
Regulation Of Immune System Process
Defense Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Mast Cell Degranulation
Positive Regulation Of Interleukin-3 Biosynthetic Process
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Regulation Of Mast Cell Activation
B Cell Receptor Signaling Pathway
Regulation Of Regulated Secretory Pathway
Response To Stress
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process
Platelet Activation
Immune System Process
Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Immune Response
Serotonin Secretion
Phagocytosis
Cell Activation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Ammonium Transport
Serotonin Transport
Innate Immune Response
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Positive Regulation Of Immune System Process
Signal Transduction
Blood Coagulation
Hemostasis
Positive Regulation Of Mast Cell Degranulation
Positive Regulation Of Mast Cell Activation
Antigen Receptor-mediated Signaling Pathway
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Signaling
Leukocyte Activation
Regulation Of Platelet Aggregation
Cell Communication
Regulation Of Exocytosis
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Regulated Secretory Pathway
Regulation Of Body Fluid Levels
Immune Response
Leukotriene Biosynthetic Process
Wound Healing
Monoamine Transport
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Immune System Process
Innate Immune Response
Regulation Of Immune Response
Regulation Of Immune System Process
Defense Response
Positive Regulation Of Immune Response
Antigen Receptor-mediated Signaling Pathway
Positive Regulation Of Cell Activation
Immune Response
Positive Regulation Of Immune System Process
Response To Stress
Cell Activation
Regulation Of Cell Activation
Fc Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Platelet Activation
Regulation Of Lymphocyte Activation
Positive Regulation Of T Cell Activation
Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Homotypic Cell-cell Adhesion
Leukocyte Migration
T Cell Receptor Signaling Pathway
Positive Regulation Of Cell-cell Adhesion
B Cell Receptor Signaling Pathway
Locomotion
T Cell Selection
Positive Regulation Of Gamma-delta T Cell Differentiation
Regulation Of T Cell Activation
Positive Regulation Of Gamma-delta T Cell Activation
T Cell Differentiation
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Gamma-delta T Cell Differentiation
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Cellular Amino Acid Metabolic Process
Positive Regulation Of Alpha-beta T Cell Proliferation
Blood Coagulation
Hemostasis
Positive Regulation Of T Cell Differentiation
Signal Transduction
Lymphocyte Differentiation
Leukocyte Activation
Positive Regulation Of Lymphocyte Differentiation
Cell Migration
Regulation Of Cellular Ketone Metabolic Process
Beta Selection
Phagocytosis
Tagcloud
?
arm
arms
benefit
carriers
concurrently
deriving
dfs
equivocal
fcgammar
fcgr2b
genotypes
genotypic
genotyping
i232t
igg1
killer
log
n9831
polymorphisms
pooled
portion
proportional
r131h
rank
sequentially
superior
trastuzumab
v158f
Tagcloud (Difference)
?
arm
arms
benefit
carriers
concurrently
deriving
dfs
equivocal
fcgammar
fcgr2b
genotypes
genotypic
genotyping
i232t
igg1
killer
log
n9831
polymorphisms
pooled
portion
proportional
r131h
rank
sequentially
superior
trastuzumab
v158f
Tagcloud (Intersection)
?