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FBP1 and HSPA8
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
HPRD
(two hybrid)
FBP1
HSPA8
Description
fructose-bisphosphatase 1
heat shock protein family A (Hsp70) member 8
Image
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Extracellular Exosome
Prp19 Complex
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Spliceosomal Complex
Nucleolus
Cytoplasm
Lysosome
Lysosomal Membrane
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Secretory Granule Lumen
Melanosome
Lysosomal Lumen
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Extracellular Exosome
Blood Microparticle
Lumenal Side Of Lysosomal Membrane
Protein Folding Chaperone Complex
Ficolin-1-rich Granule Lumen
Ribonucleoprotein Complex
Molecular Function
Catalytic Activity
Protein Binding
AMP Binding
Hydrolase Activity
Phosphatase Activity
Fructose 1,6-bisphosphate 1-phosphatase Activity
Phosphoric Ester Hydrolase Activity
Identical Protein Binding
Metal Ion Binding
Monosaccharide Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Nucleotide Binding
G Protein-coupled Receptor Binding
RNA Binding
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Enzyme Binding
MHC Class II Protein Complex Binding
Protein-macromolecule Adaptor Activity
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Protein Folding Chaperone
Cadherin Binding
Receptor Ligand Activity
Unfolded Protein Binding
Protein-folding Chaperone Binding
C3HC4-type RING Finger Domain Binding
ATP-dependent Protein Disaggregase Activity
ATP-dependent Protein Folding Chaperone
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Carbohydrate Metabolic Process
Fructose Metabolic Process
Fructose 6-phosphate Metabolic Process
Gluconeogenesis
Regulation Of Gluconeogenesis
Negative Regulation Of Cell Growth
Fructose 1,6-bisphosphate Metabolic Process
Response To Nutrient Levels
Cellular Response To Insulin Stimulus
Negative Regulation Of Glycolytic Process
Negative Regulation Of Ras Protein Signal Transduction
Cellular Response To Magnesium Ion
Cellular Response To CAMP
Cellular Response To Xenobiotic Stimulus
Cellular Hyperosmotic Salinity Response
Cellular Hypotonic Salinity Response
Cellular Response To Raffinose
Cellular Response To Phorbol 13-acetate 12-myristate
MRNA Splicing, Via Spliceosome
MRNA Processing
Protein Folding
Autophagy
Response To Unfolded Protein
Signal Transduction
RNA Splicing
Cellular Response To Starvation
Negative Regulation Of Signal Transduction
Protein Catabolic Process
Positive Regulation Of Cell Migration
Regulation Of Protein Stability
Cellular Response To Stress
Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway
Protein Refolding
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of DNA-templated Transcription
ATP Metabolic Process
Negative Regulation Of Cellular Component Organization
Membrane Organization
Regulation Of Protein Complex Stability
Chaperone-mediated Autophagy
Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy
Cellular Response To Steroid Hormone Stimulus
Clathrin Coat Disassembly
Negative Regulation Of NLRP3 Inflammasome Complex Assembly
Regulation Of Supramolecular Fiber Organization
Negative Regulation Of Supramolecular Fiber Organization
Regulation Of Protein Import
Chaperone-mediated Autophagy Translocation Complex Disassembly
Pathways
Gluconeogenesis
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
HSF1-dependent transactivation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
CHL1 interactions
AUF1 (hnRNP D0) binds and destabilizes mRNA
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
mRNA Splicing - Major Pathway
Clathrin-mediated endocytosis
Protein methylation
GABA synthesis, release, reuptake and degradation
Lipophagy
Chaperone Mediated Autophagy
Late endosomal microautophagy
Respiratory syncytial virus genome transcription
PKR-mediated signaling
Drugs
Adenosine phosphate
2,5-Anhydroglucitol-1,6-Biphosphate
{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol
Mdl-29951
Fructose-6-phosphate
MB-07803
Managlinat dialanetil
N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE
2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE
2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE
4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE
Dasatinib
(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Copper
Artenimol
Diseases
Fructose-1,6-bisphosphatase deficiency
GWAS
Cerebrospinal fluid t-tau:AB1-42 ratio (
28641921
)
Colorectal or endometrial cancer (
26621817
)
Obesity-related traits (
23251661
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular hemoglobin concentration (
29403010
32888494
)
Postoperative acute renal failure after cardiac surgery (
30678657
)
Red cell distribution width (
32888494
)
Serum metabolite levels (
33031748
)
Interacting Genes
40 interacting genes:
ACTN1
APC
ASCC2
ASL
ATP5MF
AXIN2
BCL10
BCL2L1
BIN1
BMPR1A
BRAF
BUB1
CSNK1E
CTNNA1
DCC
DNMT1
DYNC1I1
ERBB2
FLCN
FXR2
HDAC6
HSPA8
KLRC2
LNX1
MLH3
MSH2
NOTCH1
PCNX4
PIM2
POT1
PRKN
PTK2
PTPRJ
RB1
RELA
RNF183
STK11
TERF1
TLR2
TRIM28
92 interacting genes:
ABI1
AIPL1
ALDOB
APOB
ATM
BAG1
BAG2
BAG3
BAG4
BAG6
BRCA1
CCT3
CD40
CDKN2A
CITED1
CLTA
COL7A1
CXCR4
CYCS
DNAJA1
DNAJA3
DPP3
DYNLL1
EGFR
ERBB3
ERH
ESR1
FANCC
FBP1
FNDC3B
FOXP1
GAK
GCH1
GOT2
H3C1
HDAC10
HDAC3
HGS
HLTF
HSF1
HSP90AA1
HSPA1A
HSPBP1
HSPH1
HTN3
HTT
IL32
JAK2
JUN
LALBA
LINC01554
MAPK8
MAPT
NEDD8
NMI
NOA1
PHC1
PPID
PTEN
PTPRF
RAF1
RB1
REL
RGS2
RNF26
SAYSD1
SIRPA
SNCA
SP1
SRRT
ST13
STAT1
STIP1
STMN1
STUB1
SUMO2
SUMO4
TADA3
TCERG1
TGM2
TM4SF1
TNFRSF1A
TRIM38
TSSK6
TTC1
UBC
UCHL1
USP40
VHL
WEE2-AS1
YWHAG
YWHAQ
Entrez ID
2203
3312
HPRD ID
01973
07205
Ensembl ID
ENSG00000165140
ENSG00000109971
Uniprot IDs
P09467
Q2TU34
P11142
Q53HF2
V9HW22
PDB IDs
1FTA
2FHY
2FIE
2FIX
2JJK
2VT5
2WBB
2WBD
2Y5K
2Y5L
3A29
3KBZ
3KC0
3KC1
4MJO
5LDZ
5PZQ
5PZR
5PZS
5PZT
5PZU
5PZV
5PZW
5PZX
5PZY
5PZZ
5Q00
5Q01
5Q02
5Q03
5Q04
5Q05
5Q06
5Q07
5Q08
5Q09
5Q0A
5Q0B
5ZWK
6LS5
6LW2
7C9Q
7CVH
7CVN
7CWE
7EZF
7EZP
7EZR
7WJV
7WVB
8XBK
3AGY
3AGZ
3ESK
3FZF
3FZH
3FZK
3FZL
3FZM
3LDQ
3M3Z
4H5N
4H5R
4H5T
4H5V
4H5W
4HWI
4KBQ
5AQF
5AQG
5AQH
5AQI
5AQJ
5AQK
5AQL
5AQM
5AQN
5AQO
5AQP
5AQQ
5AQR
5AQS
5AQT
5AQU
5AQV
6B1I
6B1M
6B1N
6ZYJ
Enriched GO Terms of Interacting Partners
?
Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Regulation Of Nervous System Development
Regulation Of Neurogenesis
Positive Regulation Of Metabolic Process
Negative Regulation Of Developmental Process
Regulation Of Cellular Component Organization
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Development
Cellular Response To Stress
Ubiquitin Protein Ligase Binding
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Nervous System Development
Positive Regulation Of Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of Cellular Component Organization
Negative Regulation Of Apoptotic Process
Regulation Of Cell Population Proliferation
Regulation Of Primary Metabolic Process
Regulation Of Multicellular Organismal Process
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Regulation Of Protein Localization
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
Beta-catenin Binding
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cell Differentiation
Regulation Of Protein Modification Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Metabolic Process
Positive Regulation Of Multicellular Organismal Process
Anatomical Structure Morphogenesis
Positive Regulation Of Catabolic Process
Regulation Of Phosphorylation
Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Neurogenesis
Negative Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Identical Protein Binding
Positive Regulation Of Neurogenesis
Programmed Cell Death
Regulation Of Growth
Cell Death
Ubiquitin Protein Ligase Binding
Regulation Of Protein Stability
Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Protein Folding
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Protein Stabilization
Negative Regulation Of Apoptotic Process
Enzyme Binding
Response To Stress
Negative Regulation Of Programmed Cell Death
Cytosol
Apoptotic Process
Programmed Cell Death
Positive Regulation Of Macromolecule Metabolic Process
Cell Death
Positive Regulation Of Programmed Cell Death
Adenyl-nucleotide Exchange Factor Activity
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Intracellular Signal Transduction
Regulation Of Primary Metabolic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Metabolic Process
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Regulation Of Protein Modification Process
Heat Shock Protein Binding
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Multicellular Organismal Process
Hsp70 Protein Binding
Cellular Response To Stress
Regulation Of Signaling
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Communication
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Protein Folding Chaperone Complex
Negative Regulation Of Intracellular Signal Transduction
Response To Heat
Cellular Response To Oxygen-containing Compound
Negative Regulation Of Biosynthetic Process
Regulation Of Gene Expression
Positive Regulation Of Catabolic Process
Nucleus
Response To Peptide
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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