FBP1 and PCNXL4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FBP1	PCNXL4
Gene Name		fructose-1,6-bisphosphatase 1	pecanex-like 4 (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Protein Binding AMP Binding Fructose 1,6-bisphosphate 1-phosphatase Activity Identical Protein Binding Metal Ion Binding Monosaccharide Binding
	Biological Process	Carbohydrate Metabolic Process Fructose Metabolic Process Fructose 6-phosphate Metabolic Process Glucose Metabolic Process Gluconeogenesis Regulation Of Gluconeogenesis Pathogenesis Dephosphorylation Negative Regulation Of Cell Growth Cellular Response To Drug Small Molecule Metabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Ras Protein Signal Transduction Protein Homotetramerization Cellular Response To Magnesium Ion
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: ACTN1 ASCC2 ASL ATP5J2 BCL2L1 BIN1 CSNK1E DYNC1I1 FBP2 FXR2 HDAC6 HSPA8 KLRC2 LNX1 PARK2 PCNXL4 POT1 PTK2 RNF183 TERF1	3 interactors: CEP63 DISC1 FBP1
Entrez ID		2203	64430
HPRD ID		01973	16604
Ensembl ID		ENSG00000165140	ENSG00000126773
Uniprot IDs		P09467 Q2TU34	B6ZDM2 Q63HM2
PDB IDs		1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Negative Regulation Of Telomere Maintenance Via Telomerase Aggresome Assembly Positive Regulation Of Oxidative Stress-induced Cell Death Cellular Localization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Cellular Component Assembly Regulation Of Organelle Organization Negative Regulation Of Anoikis Regulation Of Telomerase Activity Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Cell Death Regulation Of Anoikis Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Telomere Maintenance Regulation Of Proteolysis RNA-dependent DNA Replication Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of DNA Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitochondrion Organization Establishment Of Localization In Cell Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cytoskeleton Organization Vesicle-mediated Transport Regulation Of Apoptotic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Cellular Response To Oxidative Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Fibril Organization Apoptotic Process In Bone Marrow Positive Regulation Of Mitochondrial Fusion Positive Regulation Of DNA Strand Elongation Hsp90 Deacetylation Positive Regulation Of Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Cellular Response To Magnesium Ion Microtubule Cytoskeleton Organization Negative Regulation Of Glycolytic Process Centriole Replication Mitochondrial Calcium Ion Homeostasis Fructose Metabolic Process Response To Magnesium Ion Regulation Of Synapse Maturation Centriole Assembly Fructose 6-phosphate Metabolic Process TOR Signaling Microtubule-based Process Regulation Of Glycolytic Process Positive Regulation Of Neuroblast Proliferation Centrosome Duplication Protein Complex Assembly Regulation Of Gluconeogenesis Cell Proliferation In Forebrain Cytoskeleton Organization Centrosome Cycle Regulation Of Neuroblast Proliferation Positive Regulation Of Neural Precursor Cell Proliferation Gluconeogenesis Cellular Response To Drug Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Cerebral Cortex Radially Oriented Cell Migration Hexose Biosynthetic Process Protein Homotetramerization Positive Regulation Of Stem Cell Proliferation Regulation Of Generation Of Precursor Metabolites And Energy Spindle Assembly Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Synapse Organization Cerebral Cortex Cell Migration Regulation Of Synapse Structure Or Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Centrosome Organization Canonical Wnt Signaling Pathway Telencephalon Cell Migration Forebrain Cell Migration Protein Tetramerization Regulation Of Glucose Metabolic Process Microtubule Organizing Center Organization Regulation Of Neural Precursor Cell Proliferation Neural Precursor Cell Proliferation Regulation Of Stem Cell Proliferation G2/M Transition Of Mitotic Cell Cycle
Tagcloud ?		abundantly albeit antagonizes bccip fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Difference) ?		abundantly albeit antagonizes bccip fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Intersection) ?