SKA1 and SKA2

Number of citations of the paper that reports this interaction (PMID 17093495)
44

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid)

		SKA1	SKA2
Gene Name		spindle and kinetochore associated complex subunit 1	spindle and kinetochore associated complex subunit 2
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Microtubule Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Regulation Of Microtubule Polymerization Or Depolymerization Cell Division	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666239)
Protein-Protein Interactions		7 interactors: AURKB BLOC1S6 LINC00521 NDC80 SKA2 SPC24 SYCE1	4 interactors: HMOX2 PRKD3 SKA1 SPC24
Entrez ID		220134	348235
HPRD ID		12689	13306
Ensembl ID		ENSG00000154839	ENSG00000182628
Uniprot IDs		Q96BD8	J3QKN8 Q8WVK7
PDB IDs		4AJ5	4AJ5
Enriched GO Terms of Interacting Partners?		Cell Division Chromosome Segregation Mitotic Nuclear Division Cell Cycle Process Attachment Of Spindle Microtubules To Kinetochore Cell Cycle Organelle Organization Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Spindle Organization Microtubule Anchoring Regulation Of Microtubule Polymerization Or Depolymerization Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Microtubule-based Process Regulation Of Microtubule-based Process Histone H3-S28 Phosphorylation Spindle Stabilization Attachment Of Mitotic Spindle Microtubules To Kinetochore Abscission Secretion Of Lysosomal Enzymes Chromosome Organization Mitotic Spindle Midzone Assembly Cleavage Furrow Formation Mitotic Spindle Elongation Endosome To Melanosome Transport Pigment Granule Maturation Synaptic Vesicle Docking Protein Localization To Kinetochore Negative Regulation Of Cytokinesis Cellular Pigment Accumulation Spindle Midzone Assembly Establishment Of Organelle Localization Protein Localization To Chromosome, Centromeric Region Negative Regulation Of B Cell Apoptotic Process Positive Regulation Of Pigment Cell Differentiation Positive Regulation Of Developmental Pigmentation Histone-serine Phosphorylation Organelle Localization Regulation Of B Cell Apoptotic Process Anterograde Synaptic Vesicle Transport Microtubule Cytoskeleton Organization Mitotic Spindle Assembly Melanosome Organization Pigment Granule Organization Synaptonemal Complex Assembly Regulation Of Developmental Pigmentation	Heme Oxidation Mitotic Nuclear Division Heme Catabolic Process Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Heme Metabolic Process Porphyrin-containing Compound Metabolic Process Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Tagcloud ?		2gammanul amo1 aspm aurkb birc5 bortezomib ccnb1 cd138 cdc2 cdc25c cenpe clonogenic downregulates epc1 hist jjn3 kifs kms myeloma possessing psma5 rpmi shi sp sps top2a ube2d3 ube3c vx
Tagcloud (Difference) ?		2gammanul amo1 aspm aurkb birc5 bortezomib ccnb1 cd138 cdc2 cdc25c cenpe clonogenic downregulates epc1 hist jjn3 kifs kms myeloma possessing psma5 rpmi shi sp sps top2a ube2d3 ube3c vx
Tagcloud (Intersection) ?