SKA2 and PRKD3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SKA2	PRKD3
Gene Name		spindle and kinetochore associated complex subunit 2	protein kinase D3
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule	Nucleoplasm Cytoplasm Membrane
	Molecular Function	Protein Binding Microtubule Binding	Protein Kinase C Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Regulation Of Microtubule Polymerization Or Depolymerization Cell Division	Protein Phosphorylation Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Intracellular Signal Transduction
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 23666239)
Protein-Protein Interactions		4 interactors: HMOX2 PRKD3 SKA1 SPC24	9 interactors: BCL6 DLAT GSK3A IKBKG KPNA2 KPNB1 NUDT3 SKA2 VAMP2
Entrez ID		348235	23683
HPRD ID		13306	06151
Ensembl ID		ENSG00000182628	ENSG00000115825
Uniprot IDs		J3QKN8 Q8WVK7	O94806
PDB IDs		4AJ5	2D9Z
Enriched GO Terms of Interacting Partners?		Heme Oxidation Mitotic Nuclear Division Heme Catabolic Process Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Heme Metabolic Process Porphyrin-containing Compound Metabolic Process Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway	Protein Import Into Nucleus Nuclear Import Protein Import NLS-bearing Protein Import Into Nucleus Protein Localization To Nucleus Protein Import Into Nucleus, Translocation Cytoplasmic Transport Nucleocytoplasmic Transport Nuclear Transport Energy Derivation By Oxidation Of Organic Compounds Intracellular Protein Transport Establishment Of Protein Localization To Organelle Regulation Of DNA Recombination Negative Regulation Of UDP-glucose Catabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Establishment Of Localization In Cell Negative Regulation Of Intracellular Signal Transduction Generation Of Precursor Metabolites And Energy Protein Targeting Protein Localization To Organelle Negative Regulation Of Type B Pancreatic Cell Development Immune Response Viral Process Cellular Localization Signaling Cellular Protein Localization Cell Communication Cellular Response To Cytokine Stimulus Negative Regulation Of Mast Cell Cytokine Production Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Eosinophil Degranulation Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Isotype Switching To IgE Isotypes Energy Reserve Metabolic Process Protein Transport Establishment Of Protein Localization Hypermethylation Of CpG Island Negative Regulation Of T-helper 2 Cell Differentiation Negative Regulation Of Cell Growth Intracellular Transport Positive Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Interleukin-3 Response To Cytokine Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Establishment Of Vesicle Localization
Tagcloud ?			advantageous characterize chimpanzee crebbp eleven ep300 evolution fgf2 germ gorilla hdac3 macaque macaques mapped microarrays orangutan organs partners primate profiled profiling proteomics regard runx1 runx2 satb2 tcf3 testis yap1
Tagcloud (Difference) ?			advantageous characterize chimpanzee crebbp eleven ep300 evolution fgf2 germ gorilla hdac3 macaque macaques mapped microarrays orangutan organs partners primate profiled profiling proteomics regard runx1 runx2 satb2 tcf3 testis yap1
Tagcloud (Intersection) ?