FARSA and RNF32

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		FARSA	RNF32
Gene Name		phenylalanyl-tRNA synthetase, alpha subunit	ring finger protein 32
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Endosome Aggresome
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Protein Binding Zinc Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation Gene Expression
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs		L-Phenylalanine
Diseases
GWAS		Red blood cell traits ( 23222517)
Protein-Protein Interactions		8 interactors: A2M ABI3 APOE ECSIT GORAB HNRNPR RNF32 TDGF1	42 interactors: A2M APOE APP BLMH CDC37 CDK5 CEP55 CYP2C8 CYP2C9 ECSIT ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 FIBP GCDH HOXC4 IFIT3 IFIT5 LONP1 LOXL4 LZTS2 MAST1 MGEA5 MKRN3 MNAT1 NOS3 PAXIP1 PRAM1 PRDX2 PSEN1 PSEN2 RAB3A RAB3D RAD23A RPP30 STAMBPL1 TRIM23 TRIM74 UBE2K
Entrez ID		2193	140545
HPRD ID		04227	11517
Ensembl ID		ENSG00000179115	ENSG00000105982
Uniprot IDs		B4E363 Q6IBR2 Q9Y285	Q9H0A6
PDB IDs		3L4G
Enriched GO Terms of Interacting Partners?		BMP Signaling Pathway Regulation Of Oxidoreductase Activity Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Regulation Of Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Complement Activation, Lectin Pathway Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Regulation Of Epithelial Cell Migration Positive Regulation Of Phospholipid Efflux Negative Regulation Of Cholesterol Biosynthetic Process Regulation Of Postsynaptic Membrane Organization Very-low-density Lipoprotein Particle Clearance Gastrulation Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Regulation Of Tau-protein Kinase Activity Negative Regulation Of Cholesterol Efflux N-methyl-D-aspartate Receptor Clustering Regulation Of Presynaptic Membrane Organization Regulation Of Catalytic Activity Negative Regulation Of Dendritic Spine Development High-density Lipoprotein Particle Clearance Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Beta-amyloid Clearance Positive Regulation Of Inclusion Body Assembly Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of Cholesterol Esterification Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering High-density Lipoprotein Particle Assembly Regulation Of Inflammatory Response Cellular Response To Hepatocyte Growth Factor Stimulus Positive Regulation Of Phospholipid Transport Chylomicron Remnant Clearance Regulation Of MAP Kinase Activity Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Triglyceride-rich Lipoprotein Particle Remodeling Stem Cell Differentiation CGMP-mediated Signaling	Catabolic Process Exocytosis Synaptic Vesicle Exocytosis Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Protein Metabolic Process Regulation Of Synaptic Plasticity Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Response To Stress Response To Stimulus Endoplasmic Reticulum Calcium Ion Homeostasis Secretion By Cell Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Protein Metabolic Process Regulation Of Receptor Activity Negative Regulation Of Cellular Protein Metabolic Process Protein Catabolic Process Cellular Response To Stimulus Establishment Of Localization In Cell Cellular Macromolecule Catabolic Process Secretion Regulation Of Neurotransmitter Levels Negative Regulation Of Protein Metabolic Process Amyloid Precursor Protein Catabolic Process Omega-hydroxylase P450 Pathway Regulation Of Protein Binding Establishment Of Protein Localization Cellular Metabolic Process Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Vesicle Docking Involved In Exocytosis Regulation Of Synaptic Transmission Intracellular Signal Transduction Positive Regulation Of Exocytosis Neurotransmitter Transport Negative Regulation Of Cell Death Neuron Death Regulation Of Protein Kinase Activity Establishment Of Organelle Localization Synapse Organization Protein Localization Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Oxidative Demethylation Regulation Of Kinase Activity Negative Regulation Of Neuron Differentiation Regulation Of ERBB Signaling Pathway
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