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RNF32 and PRDX2
Number of citations of the paper that reports this interaction (PubMedID
21163940
)
58
Data Source:
BioGRID
(two hybrid)
RNF32
PRDX2
Description
ring finger protein 32
peroxiredoxin 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endosome
Cytosol
Aggresome
Nuclear Body
Cytoplasm
Cytosol
Extracellular Exosome
Molecular Function
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Peroxidase Activity
Protein Binding
Thioredoxin Peroxidase Activity
Antioxidant Activity
Oxidoreductase Activity
Peroxiredoxin Activity
Thioredoxin-dependent Peroxiredoxin Activity
Biological Process
Defense Response To Tumor Cell
Respiratory Burst Involved In Inflammatory Response
Response To Oxidative Stress
Regulation Of Hydrogen Peroxide Metabolic Process
Removal Of Superoxide Radicals
Positive Regulation Of Blood Coagulation
Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Response To Lipopolysaccharide
Cellular Response To Oxidative Stress
T Cell Proliferation
Hydrogen Peroxide Metabolic Process
Hydrogen Peroxide Catabolic Process
Regulation Of Apoptotic Process
T Cell Homeostasis
Negative Regulation Of Apoptotic Process
Positive Regulation Of MAPK Cascade
Leukocyte Activation
Cell Redox Homeostasis
Negative Regulation Of T Cell Differentiation
Thymus Development
Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
3-sulfino-L-alanine
N-Carbamoyl-Alanine
Copper
Diseases
GWAS
Glomerular filtration rate (creatinine) (
26831199
)
Platelet distribution width (
32888494
)
Interacting Genes
42 interacting genes:
A2M
APOE
APP
BLMH
CDC37
CDK5
CEP55
CYP2C8
CYP2C9
ECSIT
ELAVL3
EXOC6
EXOSC1
FARSA
FBXL12
FBXW4
FIBP
GCDH
HOXC4
IFIT3
IFIT5
LONP1
LOXL4
LZTS2
MAST1
MKRN3
MNAT1
NOS3
OGA
PAXIP1
PRAM1
PRDX2
PSEN1
PSEN2
RAB3A
RAB3D
RAD23A
RPP30
STAMBPL1
TRIM23
TRIM74
UBE2K
24 interacting genes:
A2M
APOE
APP
BAD
CA4
CD320
CDC37
CDK1
COPS5
ECSIT
EXOC6
IFIT5
MAST1
NLGN3
PDGFRB
PPP2R1A
PPP2R1B
PSEN1
RNF32
RPL4
SAT1
SUMO4
TXNDC5
UTY
Entrez ID
140545
7001
HPRD ID
11517
02763
Ensembl ID
ENSG00000105982
ENSG00000167815
Uniprot IDs
G5E940
Q9H0A6
P32119
V9HW12
PDB IDs
1QMV
5B8A
5B8B
5IJT
7KIZ
7KJ0
7KJ1
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Amyloid Fibril Formation
Lipoprotein Particle
Catabolic Process
Acetylcholine Receptor Activator Activity
Cellular Response To Amyloid-beta
Regulation Of Amyloid Fibril Formation
Response To Amyloid-beta
Amyloid Precursor Protein Metabolic Process
Astrocyte Activation Involved In Immune Response
Caffeine Oxidase Activity
Intermediate-density Lipoprotein Particle
Growth Factor Receptor Binding
Aspartic Endopeptidase Activity, Intramembrane Cleaving
Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
Gamma-secretase Complex
Regulation Of Synaptic Plasticity
Macromolecule Catabolic Process
Oxidative Demethylation
Positive Regulation Of Regulated Secretory Pathway
Regulation Of Regulated Secretory Pathway
Omega-hydroxylase P450 Pathway
Arachidonate Epoxygenase Activity
Amyloid-beta Formation
Notch Receptor Processing
Regulation Of Proteolysis
Regulation Of Vesicle-mediated Transport
Demethylation
Synaptic Vesicle
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Postsynapse Organization
Negative Regulation Of Long-term Synaptic Potentiation
Growth Cone
Regulation Of Immune Response
Regulation Of Dendritic Spine Maintenance
Neuron Projection Maintenance
Epoxygenase P450 Pathway
Synaptic Membrane
Mitotic Cytokinesis
Low-density Lipoprotein Particle
Removal Of Superoxide Radicals
Regulation Of Blood Coagulation
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Myosin V Binding
Regulation Of Innate Immune Response
Regulation Of Hemostasis
Amyloid Precursor Protein Catabolic Process
Maintenance Of Location In Cell
Heparan Sulfate Proteoglycan Binding
Negative Regulation Of Platelet Activation
Astrocyte Activation
Positive Regulation Of Amyloid Fibril Formation
Regulation Of Amyloid Fibril Formation
Lipoprotein Particle
Regulation Of Protein Localization To Nucleus
Astrocyte Activation Involved In Immune Response
Meiotic Sister Chromatid Cohesion, Centromeric
Intermediate-density Lipoprotein Particle
Growth Factor Receptor Binding
Rough Endoplasmic Reticulum
Positive Regulation Of Protein Transport
Positive Regulation Of Protein Localization
Cellular Response To Amyloid-beta
Positive Regulation Of Apoptotic Signaling Pathway
Extracellular Exosome
Positive Regulation Of Establishment Of Protein Localization
Regulation Of Signal Transduction
Positive Regulation Of Signaling
Response To Amyloid-beta
Regulation Of Apoptotic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Meiotic Sister Chromatid Cohesion
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Long-term Synaptic Potentiation
Regulation Of Programmed Cell Death
Regulation Of Dendritic Spine Maintenance
Neuron Projection Maintenance
Enzyme Binding
Positive Regulation Of Proteolysis
Low-density Lipoprotein Particle
Regulation Of Protein Localization
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Regulation Of Apoptotic Signaling Pathway
Protein Phosphatase Type 2A Complex
Regulation Of Immune System Process
Positive Regulation Of Signal Transduction
Heparan Sulfate Proteoglycan Binding
Astrocyte Activation
Negative Regulation Of DNA Binding
Regulation Of Immune Response
Regulation Of Innate Immune Response
Very-low-density Lipoprotein Particle
Regulation Of Amyloid-beta Clearance
Regulation Of Protein Transport
Regulation Of Cell Communication
Regulation Of Signaling
Positive Regulation Of Protein Localization To Nucleus
High-density Lipoprotein Particle
Dendrite
Positive Regulation Of Glycolytic Process
Amyloid Precursor Protein Metabolic Process
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Tagcloud (Intersection)
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