RNF32 and PRAM1

Number of citations of the paper that reports this interaction (PubMedID 21163940)
58

Data Source:
BioGRID (two hybrid, pull down)

		RNF32	PRAM1
Description		ring finger protein 32	PML-RARA regulated adaptor molecule 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Aggresome Nuclear Body	Plasma Membrane Protein-containing Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Lipid Binding Protein Kinase Binding
	Biological Process		Integrin-mediated Signaling Pathway Regulation Of Neutrophil Degranulation T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Glomerular filtration rate (creatinine) ( 26831199)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Coronary artery disease ( 29212778) Height ( 18391951)
Interacting Genes		42 interacting genes: A2M APOE APP BLMH CDC37 CDK5 CEP55 CYP2C8 CYP2C9 ECSIT ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 FIBP GCDH HOXC4 IFIT3 IFIT5 LONP1 LOXL4 LZTS2 MAST1 MKRN3 MNAT1 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN1 PSEN2 RAB3A RAB3D RAD23A RPP30 STAMBPL1 TRIM23 TRIM74 UBE2K	26 interacting genes: A2M ABI2 APOE APP BCAR1 CCDC57 CDC37 CEBPA FXR1 FXR2 GOLGA2 KRT40 LCP2 LYN MAST1 MXD1 NEDD9 NEK6 PSEN1 RNF32 SH3RF1 SKAP1 SKAP2 TP53BP2 TRIM27 UBE2E2
Entrez ID		140545	84106
HPRD ID		11517	05926
Ensembl ID		ENSG00000105982	ENSG00000133246
Uniprot IDs		G5E940 Q9H0A6	Q96QH2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Amyloid Fibril Formation Lipoprotein Particle Catabolic Process Acetylcholine Receptor Activator Activity Cellular Response To Amyloid-beta Regulation Of Amyloid Fibril Formation Response To Amyloid-beta Amyloid Precursor Protein Metabolic Process Astrocyte Activation Involved In Immune Response Caffeine Oxidase Activity Intermediate-density Lipoprotein Particle Growth Factor Receptor Binding Aspartic Endopeptidase Activity, Intramembrane Cleaving Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Gamma-secretase Complex Regulation Of Synaptic Plasticity Macromolecule Catabolic Process Oxidative Demethylation Positive Regulation Of Regulated Secretory Pathway Regulation Of Regulated Secretory Pathway Omega-hydroxylase P450 Pathway Arachidonate Epoxygenase Activity Amyloid-beta Formation Notch Receptor Processing Regulation Of Proteolysis Regulation Of Vesicle-mediated Transport Demethylation Synaptic Vesicle Regulation Of Neuronal Synaptic Plasticity Regulation Of Postsynapse Organization Negative Regulation Of Long-term Synaptic Potentiation Growth Cone Regulation Of Immune Response Regulation Of Dendritic Spine Maintenance Neuron Projection Maintenance Epoxygenase P450 Pathway Synaptic Membrane Mitotic Cytokinesis Low-density Lipoprotein Particle Removal Of Superoxide Radicals Regulation Of Blood Coagulation Positive Regulation Of Membrane Protein Ectodomain Proteolysis Myosin V Binding Regulation Of Innate Immune Response Regulation Of Hemostasis Amyloid Precursor Protein Catabolic Process Maintenance Of Location In Cell Heparan Sulfate Proteoglycan Binding Negative Regulation Of Platelet Activation Astrocyte Activation	Positive Regulation Of Protein Metabolic Process Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Long-term Synaptic Potentiation SH3 Domain Binding Regulation Of Dendritic Spine Maintenance Regulation Of Immune System Process Regulation Of Neuronal Synaptic Plasticity Regulation Of Postsynapse Organization Lipoprotein Particle Regulation Of Amyloid Fibril Formation Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Regulation Of Immune Response Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Proteolysis Regulation Of Synaptic Plasticity Astrocyte Activation Involved In Immune Response Positive Regulation Of Protein Catabolic Process Intermediate-density Lipoprotein Particle Positive Regulation Of Dendritic Spine Maintenance Growth Factor Receptor Binding T Cell Receptor Signaling Pathway Memory Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Long-term Synaptic Potentiation Cytoplasm Learning Or Memory Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Amyloid-beta Signaling Receptor Activator Activity Regulation Of Amyloid Precursor Protein Catabolic Process Cytoskeleton Organization Regulation Of Synapse Organization Cytosol Supramolecular Fiber Organization Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Immune System Process Cognition Positive Regulation Of Phosphate Metabolic Process Response To Amyloid-beta Neuron Projection Positive Regulation Of Metabolic Process Regulation Of Defense Response Intracellular Signal Transduction Regulation Of Phosphorus Metabolic Process Neuron Projection Maintenance
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