RNF32 and TRIM74

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		RNF32	TRIM74
Gene Name		ring finger protein 32	tripartite motif containing 74
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Aggresome	Intracellular
	Molecular Function	Protein Binding Zinc Ion Binding	Zinc Ion Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: A2M APOE APP BLMH CDC37 CDK5 CEP55 CYP2C8 CYP2C9 ECSIT ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 FIBP GCDH HOXC4 IFIT3 IFIT5 LONP1 LOXL4 LZTS2 MAST1 MGEA5 MKRN3 MNAT1 NOS3 PAXIP1 PRAM1 PRDX2 PSEN1 PSEN2 RAB3A RAB3D RAD23A RPP30 STAMBPL1 TRIM23 TRIM74 UBE2K	11 interactors: BRCA1 LRSAM1 MGRN1 RBX1 REL RNF32 TSG101 UBE2U USP15 USP2 USP32
Entrez ID		140545	378108
HPRD ID		11517	15567
Ensembl ID		ENSG00000105982	ENSG00000155428
Uniprot IDs		Q9H0A6	Q86UV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Catabolic Process Exocytosis Synaptic Vesicle Exocytosis Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Protein Metabolic Process Regulation Of Synaptic Plasticity Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Response To Stress Response To Stimulus Endoplasmic Reticulum Calcium Ion Homeostasis Secretion By Cell Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Protein Metabolic Process Regulation Of Receptor Activity Negative Regulation Of Cellular Protein Metabolic Process Protein Catabolic Process Cellular Response To Stimulus Establishment Of Localization In Cell Cellular Macromolecule Catabolic Process Secretion Regulation Of Neurotransmitter Levels Negative Regulation Of Protein Metabolic Process Amyloid Precursor Protein Catabolic Process Omega-hydroxylase P450 Pathway Regulation Of Protein Binding Establishment Of Protein Localization Cellular Metabolic Process Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Vesicle Docking Involved In Exocytosis Regulation Of Synaptic Transmission Intracellular Signal Transduction Positive Regulation Of Exocytosis Neurotransmitter Transport Negative Regulation Of Cell Death Neuron Death Regulation Of Protein Kinase Activity Establishment Of Organelle Localization Synapse Organization Protein Localization Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Oxidative Demethylation Regulation Of Kinase Activity Negative Regulation Of Neuron Differentiation Regulation Of ERBB Signaling Pathway	Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Catabolic Process Protein Ubiquitination Cellular Protein Metabolic Process Protein Modification By Small Protein Conjugation Viral Budding Protein Deubiquitination Proteolysis Protein Modification By Small Protein Removal Protein Metabolic Process Virion Assembly Regulation Of Proteasomal Protein Catabolic Process Protein Monoubiquitination Protein Autoubiquitination Cellular Metabolic Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Ubiquitin-dependent Endocytosis Regulation Of Protein Catabolic Process Membrane Budding Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Histone H3-K9 Acetylation Histone H2B Conserved C-terminal Lysine Deubiquitination Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Regulation Of Protein Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Viral Process Negative Regulation Of Gene Expression DNA Repair Negative Regulation Of Biosynthetic Process Cellular Response To Indole-3-methanol Regulation Of Proteolysis Negative Regulation Of Centriole Replication Regulation Of Extracellular Vesicular Exosome Assembly Viral Life Cycle Dosage Compensation By Inactivation Of X Chromosome
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