FARSA

Gene Name		phenylalanyl-tRNA synthetase, alpha subunit
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation Gene Expression
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs		L-Phenylalanine
Diseases
GWAS		Red blood cell traits ( 23222517)
Protein-protein Interactions		8 interactors: A2M ABI3 APOE ECSIT GORAB HNRNPR RNF32 TDGF1
Entrez ID		2193
HPRD ID		04227
Ensembl ID		ENSG00000179115
Uniprot IDs		B4E363 Q6IBR2 Q9Y285
PDB IDs		3L4G
Enriched GO Terms of Interacting Partners?		BMP Signaling Pathway Regulation Of Oxidoreductase Activity Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Regulation Of Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Complement Activation, Lectin Pathway Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Regulation Of Epithelial Cell Migration Positive Regulation Of Phospholipid Efflux Negative Regulation Of Cholesterol Biosynthetic Process Regulation Of Postsynaptic Membrane Organization Very-low-density Lipoprotein Particle Clearance Gastrulation Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Regulation Of Tau-protein Kinase Activity Negative Regulation Of Cholesterol Efflux N-methyl-D-aspartate Receptor Clustering Regulation Of Presynaptic Membrane Organization Regulation Of Catalytic Activity Negative Regulation Of Dendritic Spine Development High-density Lipoprotein Particle Clearance Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Beta-amyloid Clearance Positive Regulation Of Inclusion Body Assembly Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of Cholesterol Esterification Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering High-density Lipoprotein Particle Assembly Regulation Of Inflammatory Response Cellular Response To Hepatocyte Growth Factor Stimulus Positive Regulation Of Phospholipid Transport Chylomicron Remnant Clearance Regulation Of MAP Kinase Activity Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Triglyceride-rich Lipoprotein Particle Remodeling Stem Cell Differentiation CGMP-mediated Signaling
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