FANCE and FANCC

Number of citations of the paper that reports this interaction (PubMedID 11157805)
0

Data Source:
HPRD (two hybrid)

		FANCE	FANCC
Description		FA complementation group E	FA complementation group C
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Centrosome Cytosol Fanconi Anaemia Nuclear Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Ovarian Follicle Development DNA Repair DNA Damage Response Gene Expression Interstrand Cross-link Repair Homeostasis Of Number Of Cells	DNA Repair Nucleotide-excision Repair DNA Damage Response Cellular Response To Oxidative Stress Interstrand Cross-link Repair Protein-containing Complex Assembly
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes PKR-mediated signaling
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Height ( 28552196) Ovarian cancer ( 30557369) Pulmonary function (smoking interaction) ( 23284291)	Birth weight ( 31043758) Hematocrit ( 32888494) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		8 interacting genes: BRCA2 CHEK1 FANCA FANCC FANCD2 FANCF FANCG HES1	54 interacting genes: APC AZIN1 BMPR1A BUB1 CAPN10 CCNA2 CCND1 CDK1 CTBP1 DLC1 DNAJB1 EGFR FANCA FANCD2 FANCE FANCF FANCG FBXW7 GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRAS KRT1 MEOX2 MLH3 MT-ATP6 MUTYH NRAS PDGFRL PIK3CA PMS2 POR PRDX3 PRPF31 PTPN12 PTPRJ RB1 RPL18 RPS3A SMAD4 SPTA1 SPTAN1 SRC STAT1 STMN1 STMN2 TCERG1 TGFBR2 USP14 ZBTB32
Entrez ID		2178	2176
HPRD ID		02943	01967
Ensembl ID		ENSG00000112039	ENSG00000158169
Uniprot IDs		A0A8Q3WL50 A0A8Q3WMB8 Q9HB96	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs		2ILR 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
Enriched GO Terms of Interacting Partners?		Interstrand Cross-link Repair Fanconi Anaemia Nuclear Complex DNA Repair DNA Metabolic Process DNA Damage Response Chromatin Cellular Response To Stress Nucleic Acid Metabolic Process Regulation Of CD40 Signaling Pathway Nucleoplasm Nucleobase-containing Compound Metabolic Process DNA Repair Complex Inner Cell Mass Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Signal Transduction In Response To DNA Damage Regulation Of Mitotic Cell Cycle Response To Stress Neuronal Stem Cell Population Maintenance Female Gonad Development Regulation Of Regulatory T Cell Differentiation Male Meiotic Nuclear Division Nucleotide-excision Repair Response To Gamma Radiation BRCA2-MAGE-D1 Complex Nucleus Positive Regulation Of Cell Cycle Mitotic DNA Damage Checkpoint Signaling Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Mitotic DNA Integrity Checkpoint Signaling Meiotic Nuclear Division Regulation Of T Cell Activation Mitotic Recombination-dependent Replication Fork Processing Nuclear Division Response To Radiation Macromolecule Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle DNA Damage Checkpoint Signaling Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Histone H3T11 Kinase Activity Regulation Of Lymphocyte Activation	Cytosol Regulation Of Programmed Cell Death Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Negative Regulation Of Supramolecular Fiber Organization Cellular Response To Stress Response To Stress Cellular Response To Growth Factor Stimulus Negative Regulation Of Cellular Component Organization Negative Regulation Of Cytoskeleton Organization Response To Hormone Response To Growth Factor Fanconi Anaemia Nuclear Complex Cellular Response To Peptide Hormone Stimulus ATP-dependent Protein Folding Chaperone Cellular Response To Hormone Stimulus Interstrand Cross-link Repair Nucleoplasm Regulation Of Supramolecular Fiber Organization Response To Steroid Hormone Regulation Of Organelle Organization Negative Regulation Of Programmed Cell Death Cadherin Binding Positive Regulation Of Cell Population Proliferation Nucleus Focal Adhesion Protein Folding Chaperone Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Regulation Of Multicellular Organismal Process DNA Repair Regulation Of Immune System Process Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein-containing Complex Disassembly DNA Damage Response Intracellular Signal Transduction Response To Peptide Hormone Regulation Of Cytoskeleton Organization Response To Lipid G1/S Transition Of Mitotic Cell Cycle Nucleic Acid Metabolic Process Macromolecule Metabolic Process Regulation Of Protein-containing Complex Assembly Negative Regulation Of Cell Cycle Phase Transition Cell Cycle G1/S Phase Transition Response To Unfolded Protein Regulation Of Cellular Component Organization Regulation Of Cell Cycle Phase Transition Regulation Of Protein Depolymerization
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