FANCE and FANCD2

Number of citations of the paper that reports this interaction (PMID 12093742)
24

Data Source:
HPRD (two hybrid)

		FANCE	FANCD2
Gene Name		Fanconi anemia, complementation group E	Fanconi anemia, complementation group D2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Fanconi Anaemia Nuclear Complex	Condensed Chromosome Nucleoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function	Protein Binding DNA Polymerase Binding
	Biological Process	DNA Repair	DNA Repair Synapsis Gamete Generation Response To Gamma Radiation
Pathways		Fanconi Anemia pathway	Fanconi Anemia pathway Regulation of the Fanconi anemia pathway
Drugs
Diseases
GWAS		Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		8 interactors: BRCA2 CHEK1 FANCA FANCC FANCD2 FANCF FANCG HES1	20 interactors: ATM ATR BLM BRCA1 BRCA2 FANCC FANCE FANCI FANCL MEN1 MRE11A NBN PCNA RAD51 TERF1 TNFRSF1A TNFRSF1B TNKS UBB USP1
Entrez ID		2178	2177
HPRD ID		02943	01968
Ensembl ID		ENSG00000112039	ENSG00000144554
Uniprot IDs		Q9HB96	Q9BXW9
PDB IDs		2ILR
Enriched GO Terms of Interacting Partners?		DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Reproductive Process Developmental Process Involved In Reproduction Female Gonad Development Cellular Response To Stress Development Of Primary Female Sexual Characteristics Reproduction Reproductive Structure Development Reproductive System Development Gonad Development Development Of Primary Sexual Characteristics Gamete Generation Sex Differentiation Nucleobase-containing Compound Metabolic Process Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Nitrogen Compound Metabolic Process Response To Stress Meiotic Nuclear Division Cell Cycle Meiotic Cell Cycle Cellular Response To Stimulus Germ Cell Development Response To Gamma Radiation Male Meiosis Response To Stimulus Cell Cycle Process Developmental Process Ovarian Follicle Development Cell Aging Regulation Of Mitotic Cell Cycle Response To Abiotic Stimulus Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Nucleotide-excision Repair Negative Regulation Of DNA Metabolic Process Ovulation Cycle Process Spermatogenesis Male Gamete Generation Meiosis I	Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Regulation Of DNA Replication Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cell Cycle DNA Recombination Cell Cycle Process Response To Stress Double-strand Break Repair Negative Regulation Of DNA Replication Cell Cycle Checkpoint Response To Ionizing Radiation DNA Damage Checkpoint Telomere Maintenance DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process G2 DNA Damage Checkpoint Negative Regulation Of DNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Stimulus Nitrogen Compound Metabolic Process Response To Stimulus Mitotic G2 DNA Damage Checkpoint Regulation Of Protein Metabolic Process Response To Radiation Negative Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Checkpoint Response To Abiotic Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Cellular Metabolic Process Signal Transduction In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Signal Transduction By P53 Class Mediator Mitotic Cell Cycle Process Chromosome Organization Regulation Of Response To DNA Damage Stimulus Mitotic Cell Cycle
Tagcloud ?		chek2 clk2 comprehensively escc esophageal fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted	10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
Tagcloud (Difference) ?		chek2 clk2 comprehensively escc esophageal fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted	10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
Tagcloud (Intersection) ?