FAH and KRTAP5-9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAH	KRTAP5-9
Gene Name		fumarylacetoacetate hydrolase (fumarylacetoacetase)	keratin associated protein 5-9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Keratin Filament
	Molecular Function	Fumarylacetoacetase Activity Metal Ion Binding	Protein Binding
	Biological Process	Arginine Catabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process	Epidermis Development
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ADAMTSL4 EGFR KRTAP10-8 KRTAP5-9 SERTAD1 TCF4	103 interactors: ADAMTSL4 ALPP ATG9A BEX2 BMP7 C10orf62 C11orf87 C19orf66 CARKD CATSPER1 CHIC2 CHRD CKS1B CNNM3 COMT CRCT1 CTSZ CXCL16 DHRS1 DMRT3 DOCK2 FAH FAM124B FAM161A FAM74A4 FAM76B GLRX3 GNE HOXA1 HOXB9 HPCAL1 HSPD1 JOSD1 KLHL38 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE3C LCE3E LCE4A LY6H MAPKBP1 MEOX2 NCLN NLK NMU NOTCH2NL NPBWR2 NPDC1 NTM NTN4 NUFIP2 OTX1 P2RX4 PCSK5 PFKL PGLS POM121L8P PRKAB2 PSMA1 PTPMT1 PVRL2 RAMP3 RGS20 RNF111 SCARB1 SDC3 SDCBP SLC22A23 SLC25A10 SMCP SPINK2 SPRY2 TBC1D10C TBC1D16 TCEA2 TCEANC TOMM22 TYRO3 WDYHV1 YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF266 ZNF417 ZNF439 ZNF581 ZNF587
Entrez ID		2184	3846
HPRD ID		02040	01008
Ensembl ID		ENSG00000103876	ENSG00000254997
Uniprot IDs		P16930	P26371
PDB IDs
Enriched GO Terms of Interacting Partners?		Digestive Tract Morphogenesis Positive Regulation Of Protein Kinase B Signaling Regulation Of Smooth Muscle Cell Proliferation Glial Cell Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Nucleocytoplasmic Transport Alkanesulfonate Metabolic Process Regulation Of Protein Kinase B Signaling Digestive Tract Development Digestive System Development Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Catenin Import Into Nucleus Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Astrocyte Activation Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Cycle Glial Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Nucleocytoplasmic Transport Activation Of Phospholipase A2 Activity Maintenance Of DNA Repeat Elements Skin Development Epithelium Development Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Intracellular Transport Gliogenesis Response To Cobalamin Response To UV-A Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Hindgut Morphogenesis Regulation Of Intracellular Protein Transport Epidermis Development Embryonic Genitalia Morphogenesis Response To Hydroxyisoflavone Ossification Regulation Of Epithelial Cell Proliferation Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Myoblast Fate Commitment Positive Regulation Of Transcription, DNA-templated Secretory Granule Localization Positive Regulation Of Protein Transport Positive Regulation Of Catenin Import Into Nucleus Regulation Of Apoptotic Process Regulation Of Cell Proliferation Hindgut Morphogenesis Protein O-linked Fucosylation Positive Regulation Of Macromolecule Biosynthetic Process	Keratinization Keratinocyte Differentiation Pattern Specification Process Epidermal Cell Differentiation Developmental Process Positive Regulation Of Immune Response To Tumor Cell Adhesion Of Symbiont To Host Locomotion Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy Organ Development Cell Recognition Skin Development Multicellular Organismal Development Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Anterior/posterior Pattern Specification Cell Differentiation System Development Epidermis Development Transcription, DNA-templated
Tagcloud ?		adequately alcoholic busulfan chimeric chimerism conditioning enabling examples exceeded fails frgn fumarylacetoacetate hematolymphoid hepatocytes hepatotoxicity hepatotropic humanization humanized hydrolase il2rg involve kupffer livers pathophysiologic rag2 repopulation steatohepatitis transplanted upa
Tagcloud (Difference) ?		adequately alcoholic busulfan chimeric chimerism conditioning enabling examples exceeded fails frgn fumarylacetoacetate hematolymphoid hepatocytes hepatotoxicity hepatotropic humanization humanized hydrolase il2rg involve kupffer livers pathophysiologic rag2 repopulation steatohepatitis transplanted upa
Tagcloud (Intersection) ?