FAH

Gene Name		fumarylacetoacetate hydrolase (fumarylacetoacetase)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Fumarylacetoacetase Activity Metal Ion Binding
	Biological Process	Arginine Catabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: ADAMTSL4 EGFR KRTAP10-8 KRTAP5-9 SERTAD1 TCF4
Entrez ID		2184
HPRD ID		02040
Ensembl ID		ENSG00000103876
Uniprot IDs		P16930
PDB IDs
Enriched GO Terms of Interacting Partners?		Digestive Tract Morphogenesis Positive Regulation Of Protein Kinase B Signaling Regulation Of Smooth Muscle Cell Proliferation Glial Cell Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Nucleocytoplasmic Transport Alkanesulfonate Metabolic Process Regulation Of Protein Kinase B Signaling Digestive Tract Development Digestive System Development Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Catenin Import Into Nucleus Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Astrocyte Activation Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Cycle Glial Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Nucleocytoplasmic Transport Activation Of Phospholipase A2 Activity Maintenance Of DNA Repeat Elements Skin Development Epithelium Development Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Intracellular Transport Gliogenesis Response To Cobalamin Response To UV-A Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Hindgut Morphogenesis Regulation Of Intracellular Protein Transport Epidermis Development Embryonic Genitalia Morphogenesis Response To Hydroxyisoflavone Ossification Regulation Of Epithelial Cell Proliferation Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Myoblast Fate Commitment Positive Regulation Of Transcription, DNA-templated Secretory Granule Localization Positive Regulation Of Protein Transport Positive Regulation Of Catenin Import Into Nucleus Regulation Of Apoptotic Process Regulation Of Cell Proliferation Hindgut Morphogenesis Protein O-linked Fucosylation Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		adequately alcoholic busulfan chimeric chimerism conditioning enabling examples exceeded fails frgn fumarylacetoacetate hematolymphoid hepatocytes hepatotoxicity hepatotropic humanization humanized hydrolase il2rg involve kupffer livers pathophysiologic rag2 repopulation steatohepatitis transplanted upa