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FAH

Description fumarylacetoacetate hydrolase
Image No pdb structure
GO Annotations Cellular Component
  • Cytosol
  • Extracellular Exosome
Molecular Function
  • Catalytic Activity
  • Fumarylacetoacetase Activity
  • Protein Binding
  • Hydrolase Activity
  • Metal Ion Binding
Biological Process
  • L-arginine Catabolic Process
  • L-phenylalanine Catabolic Process
  • L-tyrosine Catabolic Process
  • Lipid Metabolic Process
  • Aromatic Amino Acid Metabolic Process
  • Homogentisate Catabolic Process
Pathways
  • Tyrosine catabolism
Drugs
  • Fumaric acid
  • Acetoacetic acid
  • 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
Diseases
  • Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
GWAS
  • Blood protein levels ( 30072576)
Novel Interacting Genes 1 novel interacting genes: ETFA
Interacting Genes 9 interacting genes: ADAMTSL4 CHRDL2 EGFR KRTAP10-8 KRTAP13-3 KRTAP5-9 PLEKHF2 SERTAD1 TCF4
Entrez ID 2184
HPRD ID 02040
Ensembl ID ENSG00000103876
Uniprot IDs A0A384P5L6 P16930
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Intermediate Filament
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025