FAH and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAH	SERTAD1
Description		fumarylacetoacetate hydrolase	SERTA domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Cytoplasm Sarcoplasm
	Molecular Function	Catalytic Activity Fumarylacetoacetase Activity Protein Binding Hydrolase Activity Metal Ion Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	L-arginine Catabolic Process L-phenylalanine Catabolic Process L-tyrosine Catabolic Process Lipid Metabolic Process Aromatic Amino Acid Metabolic Process Homogentisate Catabolic Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Tyrosine catabolism
Drugs		Fumaric acid Acetoacetic acid 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
Diseases		Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
GWAS		Blood protein levels ( 30072576)	Monocyte percentage of white cells ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		9 interacting genes: ADAMTSL4 CHRDL2 EGFR KRTAP10-8 KRTAP13-3 KRTAP5-9 PLEKHF2 SERTAD1 TCF4	56 interacting genes: ADCY1 AIRIM ASB8 ATG12 ATXN7L3 BANF2 CCND2 CDK4 CDKN2A CHAF1A CHURC1 CIB3 CINP CKS1B COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAAP20 FAH FNDC11 FXR1 GLYCTK HIVEP1 HSPB1 KAT2B KLC4 KLHL42 MVP P4HA3 PATE1 PBX4 PICK1 PIH1D2 POT1 PRDM4 PSORS1C2 RBX1 RCHY1 ROPN1 SEC14L4 SETD7 SFI1 SMAD3 SPEN SSX7 STAT5B SUPT7L TGM2 TLR4 TRIM28 TSC1 XIAP ZNF410
Entrez ID		2184	29950
HPRD ID		02040	15326
Ensembl ID		ENSG00000103876	ENSG00000197019
Uniprot IDs		A0A384P5L6 P16930	Q53GC0 Q9UHV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament	N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Macromolecule Biosynthetic Process P53 Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress RNA Polymerase II-specific DNA-binding Transcription Factor Binding Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Histone H3K27 Acetyltransferase Activity Regulation Of DNA Repair Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Protein Localization To Nucleus Protein Binding Cellular Response To Stress Cyclin D2-CDK4 Complex Acetyltransferase Activity Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Nucleus Protein Modification Process DNA Damage Response Canonical NF-kappaB Signal Transduction Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Histone Acetyltransferase Complex Transcription Coregulator Activity SAGA Complex Protein-lysine-acetyltransferase Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Stabilization Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Chromatin Regulation Of Protein Localization To Nucleus Chromatin Binding Histone Acetyltransferase Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Chromo Shadow Domain Binding Protein Acetylation Cellular Response To Nutrient Levels Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Positive Regulation Of Protein Import Into Nucleus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?