FAH and SERTAD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAH	SERTAD1
Gene Name		fumarylacetoacetate hydrolase (fumarylacetoacetase)	SERTA domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Fumarylacetoacetase Activity Metal Ion Binding	Protein Binding
	Biological Process	Arginine Catabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription, DNA-templated
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ADAMTSL4 EGFR KRTAP10-8 KRTAP5-9 SERTAD1 TCF4	36 interactors: ASB8 ATXN7L3 CCND2 CDK4 CDKN2A CHURC1 CIB3 COPB1 CREBBP DENND4A EGLN3 EP300 FAH HIVEP1 HSPB1 KAT2B KLHL42 MVP P4HA3 PATE1 POT1 PRDM4 RBX1 RCHY1 ROPN1 SETD7 SFI1 SMAD3 SPEN STAT5B SUPT7L TCEB1 TGM2 TLR4 TRIM28 ZNF410
Entrez ID		2184	29950
HPRD ID		02040	15326
Ensembl ID		ENSG00000103876
Uniprot IDs		P16930	Q53GC0 Q9UHV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Digestive Tract Morphogenesis Positive Regulation Of Protein Kinase B Signaling Regulation Of Smooth Muscle Cell Proliferation Glial Cell Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Nucleocytoplasmic Transport Alkanesulfonate Metabolic Process Regulation Of Protein Kinase B Signaling Digestive Tract Development Digestive System Development Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Catenin Import Into Nucleus Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Astrocyte Activation Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Cycle Glial Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Nucleocytoplasmic Transport Activation Of Phospholipase A2 Activity Maintenance Of DNA Repeat Elements Skin Development Epithelium Development Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Intracellular Transport Gliogenesis Response To Cobalamin Response To UV-A Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Hindgut Morphogenesis Regulation Of Intracellular Protein Transport Epidermis Development Embryonic Genitalia Morphogenesis Response To Hydroxyisoflavone Ossification Regulation Of Epithelial Cell Proliferation Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Myoblast Fate Commitment Positive Regulation Of Transcription, DNA-templated Secretory Granule Localization Positive Regulation Of Protein Transport Positive Regulation Of Catenin Import Into Nucleus Regulation Of Apoptotic Process Regulation Of Cell Proliferation Hindgut Morphogenesis Protein O-linked Fucosylation Positive Regulation Of Macromolecule Biosynthetic Process	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Gene Expression Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Response To Hypoxia Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Cellular Protein Modification Process Macromolecule Biosynthetic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Oxygen Levels N-terminal Protein Amino Acid Acetylation Viral Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Notch Signaling Pathway Negative Regulation Of Cellular Metabolic Process Cellular Protein Metabolic Process Peptidyl-amino Acid Modification Protein Metabolic Process Chromatin Organization Chromosome Organization Positive Regulation Of Interleukin-1 Production N-terminal Protein Amino Acid Modification Positive Regulation Of Cytokine Production Response To Abiotic Stimulus
Tagcloud ?		adequately alcoholic busulfan chimeric chimerism conditioning enabling examples exceeded fails frgn fumarylacetoacetate hematolymphoid hepatocytes hepatotoxicity hepatotropic humanization humanized hydrolase il2rg involve kupffer livers pathophysiologic rag2 repopulation steatohepatitis transplanted upa
Tagcloud (Difference) ?		adequately alcoholic busulfan chimeric chimerism conditioning enabling examples exceeded fails frgn fumarylacetoacetate hematolymphoid hepatocytes hepatotoxicity hepatotropic humanization humanized hydrolase il2rg involve kupffer livers pathophysiologic rag2 repopulation steatohepatitis transplanted upa
Tagcloud (Intersection) ?