ALB and RYR2

Number of citations of the paper that reports this interaction (PubMedID 15174051)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		ALB	RYR2
Description		albumin	ryanodine receptor 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Platelet Alpha Granule Lumen Protein-containing Complex Extracellular Exosome Blood Microparticle	Smooth Endoplasmic Reticulum Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Sarcomere Z Disc Protein-containing Complex Sarcoplasmic Reticulum Membrane Calcium Channel Complex Sarcolemma
	Molecular Function	DNA Binding Fatty Acid Binding Copper Ion Binding Protein Binding Lipid Binding Toxic Substance Binding Antioxidant Activity Oxygen Binding Pyridoxal Phosphate Binding Identical Protein Binding Metal Ion Binding Protein-folding Chaperone Binding Exogenous Protein Binding Enterobactin Binding	Monoatomic Ion Channel Activity Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Activity Calcium Ion Binding Protein Binding Calmodulin Binding Intracellularly Gated Calcium Channel Activity Enzyme Binding Protein Kinase Binding Protein Kinase A Catalytic Subunit Binding Protein Kinase A Regulatory Subunit Binding Identical Protein Binding Suramin Binding Transmembrane Transporter Binding Calcium-induced Calcium Release Activity
	Biological Process	Cellular Response To Starvation Response To Nutrient Levels Negative Regulation Of Mitochondrial Depolarization Cellular Response To Calcium Ion Starvation Cellular Oxidant Detoxification	Response To Hypoxia Regulation Of Heart Rate Embryonic Heart Tube Morphogenesis Left Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Hypertrophy Detection Of Calcium Ion Monoatomic Ion Transport Calcium Ion Transport Intracellular Calcium Ion Homeostasis Striated Muscle Contraction Positive Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To Muscle Activity Calcium-mediated Signaling Response To Caffeine Monoatomic Ion Transmembrane Transport Response To Muscle Stretch Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Cytosolic Calcium Ion Concentration Establishment Of Localization In Cell Response To Redox State Transmembrane Transport Regulation Of Cardiac Muscle Contraction Cardiac Muscle Contraction Calcium Ion Transport Into Cytosol Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Cellular Response To Caffeine Cellular Response To Epinephrine Stimulus Establishment Of Protein Localization To Endoplasmic Reticulum Ventricular Cardiac Muscle Cell Action Potential Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Cell Communication By Electrical Coupling Involved In Cardiac Conduction Type B Pancreatic Cell Apoptotic Process Calcium Ion Transmembrane Import Into Cytosol Positive Regulation Of The Force Of Heart Contraction Regulation Of AV Node Cell Action Potential Regulation Of SA Node Cell Action Potential Regulation Of Atrial Cardiac Muscle Cell Action Potential Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways		Platelet degranulation Recycling of bile acids and salts Heme biosynthesis Heme degradation Scavenging of heme from plasma Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation HDL remodeling Cytoprotection by HMOX1 Aspirin ADME Prednisone ADME Ciprofloxacin ADME	Stimuli-sensing channels Ion homeostasis
Drugs		Amsacrine Cefotaxime Phenol Norelgestromin Aniline Guaiacol Artenimol Silver Patent Blue	Flecainide Tetracaine
Diseases			Catecholaminergic polymorphic ventricular tachycardia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS		Cholesterol ester levels in large LDL ( 29084231) Cholesterol ester levels in medium LDL ( 29084231) Esterified cholesterol levels ( 29084231) Free cholesterol levels ( 29084231) Free cholesterol levels in large LDL ( 29084231) Large LDL particle concentration ( 29084231) Lipid metabolism phenotypes ( 22286219) Medium LDL particle concentration ( 29084231) Prostate cancer ( 23535732) Serum total cholesterol levels ( 29084231) Small LDL particle concentration ( 29084231) Total cholesterol levels in large LDL ( 29084231) Total cholesterol levels in LDL ( 29084231) Total cholesterol levels in medium LDL ( 29084231) Total cholesterol levels in small LDL ( 29084231)	Acute lymphoblastic leukemia (childhood) ( 19684603) Bipolar disorder and eating disorder ( 26433762) Cerivastatin-induced rhabdomyolysis ( 21386754) cognitive impairment (MMSE score) in Parkinson’s disease ( 33613413) Exercise treadmill test traits ( 17903301) General risk tolerance (MTAG) ( 30643258) Hippocampal volume ( 31530798) Hypertension ( 17554300) Lipid traits ( 24386095 30576415) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Postoperative stroke after cardiac surgery ( 30678657) PR interval ( 32439900) Response to taxane treatment (docetaxel) ( 23006423) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		32 interacting genes: AGA AMBP APOE CRYAA CUBN F7 FCGRT FNDC3B FOXP1 HNF1A IMMT KLK3 LAMTOR5 LINC00624 LINC02582 LRP2 LUC7L2 NR5A2 ORM1 PFDN1 PON1 PRB3 RBP4 RNF181 RYR2 SRGN ST13 TK1 USP7 VWF WEE2-AS1 YWHAG	21 interacting genes: AKAP6 ALB CACNA1C CACNA1D FKBP1B HOMER1 HSPB2 ITPR1 JPH3 JPH4 KCNN4 LINC00839 MDM2 PRKACA PRKAR2A PSEN1 RYR1 RYR3 SMAD5 SRI UBE2C
Entrez ID		213	6262
HPRD ID		00062	01619
Ensembl ID		ENSG00000163631	ENSG00000198626
Uniprot IDs		P02768	Q92736
PDB IDs		1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1HK5 1N5U 1O9X 1TF0 1UOR 1YSX 2BX8 2BXA 2BXB 2BXC 2BXD 2BXE 2BXF 2BXG 2BXH 2BXI 2BXK 2BXL 2BXM 2BXN 2BXO 2BXP 2BXQ 2ESG 2I2Z 2I30 2N0X 2VDB 2VUE 2VUF 2XSI 2XVQ 2XVU 2XVV 2XVW 2XW0 2XW1 2YDF 3A73 3B9L 3B9M 3CX9 3JQZ 3JRY 3LU6 3LU7 3LU8 3SQJ 3TDL 3UIV 4BKE 4E99 4EMX 4G03 4G04 4HGK 4HGM 4IW1 4IW2 4K2C 4K71 4L8U 4L9K 4L9Q 4LA0 4LB2 4LB9 4N0F 4N0U 4S1Y 4Z69 5FUO 5GIX 5GIY 5ID7 5IFO 5IJF 5UJB 5VNW 5X52 5YB1 5YOQ 5Z0B 6A7P 6EZQ 6JE7 6L4K 6M4R 6M58 6M5D 6M5E 6QIO 6QIP 6R7S 6WUW 6XV0 6YG9 6ZL1 7A9C 7AAE 7AAI 7D6J 7DJN 7DL4 7EEK 7FFR 7FFS 7JWN 7QFE 7VR0 7VR9 7WKZ 7WLF 7WOJ 7WOK 7WZ9 7X7X 7Y2D 7Z57 8A9Q 8CKS 8EW4 8EW7 8EY5 8H0O 8ISM 8ITR 8ITT 8J8E 8K1Y 8OI2 8Q3F 8RCO 8RCP 8RGK 8RGL 8VAC 8VAE 8VAF 8Y9S 8Y9T 8Y9U 8YG7 8YXA 8YXB 8Z8V 9CSG	4JKQ 6Y4O 6Y4P 7KL5 7U9Q 7U9R 7U9T 7U9X 7U9Z 7UA1 7UA3 7UA4 7UA5 7UA9 8UQ2 8UQ3 8UQ4 8UQ5 8UXC 8UXE 8UXF 8UXG 8UXH 8UXI 8UXL 8UXM
Enriched GO Terms of Interacting Partners?		Steroid Metabolic Process Protein-containing Complex Vascular Endothelial Growth Factor Binding Extracellular Space Blood Microparticle Negative Regulation Of Multicellular Organismal Process Vascular Endothelial Growth Factor Receptor Activity Genitalia Development Vitamin Transport Cobalamin Transport Vagina Development Alcohol Metabolic Process Regulation Of Biological Quality Regulation Of Multicellular Organismal Process Regulation Of TOR Signaling Response To Reactive Oxygen Species Platelet Alpha Granule Lumen TORC1 Signaling Negative Regulation Of Amyloid Fibril Formation Regulation Of Blood Coagulation Regulation Of Hemostasis Extracellular Region Regulation Of Defense Response To Bacterium Female Genitalia Development Vitamin Transmembrane Transport Regulation Of Amyloid Fibril Formation Negative Regulation Of Platelet Activation Transcytosis Receptor Complex Vascular Endothelial Growth Factor Signaling Pathway TOR Signaling U1 SnRNP Positive Regulation Of TOR Signaling Cytochrome C Metabolic Process Antioxidant Activity Extracellular Matrix Extracellular Exosome Negative Regulation Of Phospholipid Efflux Sterol Metabolic Process Chemical Homeostasis Negative Regulation Of Gene Expression High-density Lipoprotein Particle Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Cholesterol Metabolic Process Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Positive Regulation Of Multicellular Organismal Process Calcium Ion Homeostasis Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway	Regulation Of Sequestering Of Calcium Ion Calcium Ion Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transport Calcium Ion Transmembrane Import Into Cytosol Calcium Ion Transmembrane Transport Regulation Of Metal Ion Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Calcium Ion Transmembrane Transport Regulation Of Monoatomic Cation Transmembrane Transport Calcium-mediated Signaling Regulation Of Monoatomic Ion Transport Metal Ion Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Heart Contraction Calcium Channel Complex Z Disc Sarcoplasmic Reticulum Monoatomic Cation Transport Junctional Sarcoplasmic Reticulum Membrane Regulation Of Blood Circulation Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Cardiac Muscle Contraction Calcium Channel Activity Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport System Process Regulation Of Striated Muscle Contraction Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Ion Transmembrane Transport Muscle Contraction Regulation Of Transport Monoatomic Ion Transmembrane Transport Regulation Of System Process Smooth Endoplasmic Reticulum Regulation Of Muscle System Process Muscle System Process Regulation Of Muscle Contraction Protein Tetramerization Sarcoplasmic Reticulum Membrane Intracellularly Gated Calcium Channel Activity Intracellular Signal Transduction T-tubule Positive Regulation Of Transport Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Intracellular Signaling Cassette Calcium Ion Transport Into Cytosol Regulation Of Protein Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?