ALB and SRGN

Number of citations of the paper that reports this interaction (PubMedID 4062880)
12

Data Source:
HPRD (in vitro)

		ALB	SRGN
Description		albumin	serglycin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Platelet Alpha Granule Lumen Protein-containing Complex Extracellular Exosome Blood Microparticle	Extracellular Region Extracellular Space Lysosome Golgi Apparatus Secretory Granule Extracellular Matrix Platelet Alpha Granule Lumen Mast Cell Granule Cytolytic Granule
	Molecular Function	DNA Binding Fatty Acid Binding Copper Ion Binding Protein Binding Lipid Binding Toxic Substance Binding Antioxidant Activity Oxygen Binding Pyridoxal Phosphate Binding Identical Protein Binding Metal Ion Binding Protein-folding Chaperone Binding Exogenous Protein Binding Enterobactin Binding	Protein Binding
	Biological Process	Cellular Response To Starvation Response To Nutrient Levels Negative Regulation Of Mitochondrial Depolarization Cellular Response To Calcium Ion Starvation Cellular Oxidant Detoxification	Negative Regulation Of Cytokine Production Apoptotic Process Protein Processing Negative Regulation Of Bone Mineralization Biomineral Tissue Development Secretory Granule Organization Mast Cell Secretory Granule Organization T Cell Secretory Granule Organization Maintenance Of Protease Location In Mast Cell Secretory Granule Maintenance Of Granzyme B Location In T Cell Secretory Granule Granzyme-mediated Programmed Cell Death Signaling Pathway
Pathways		Platelet degranulation Recycling of bile acids and salts Heme biosynthesis Heme degradation Scavenging of heme from plasma Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation HDL remodeling Cytoprotection by HMOX1 Aspirin ADME Prednisone ADME Ciprofloxacin ADME	Platelet degranulation
Drugs		Amsacrine Cefotaxime Phenol Norelgestromin Aniline Guaiacol Artenimol Silver Patent Blue
Diseases
GWAS		Cholesterol ester levels in large LDL ( 29084231) Cholesterol ester levels in medium LDL ( 29084231) Esterified cholesterol levels ( 29084231) Free cholesterol levels ( 29084231) Free cholesterol levels in large LDL ( 29084231) Large LDL particle concentration ( 29084231) Lipid metabolism phenotypes ( 22286219) Medium LDL particle concentration ( 29084231) Prostate cancer ( 23535732) Serum total cholesterol levels ( 29084231) Small LDL particle concentration ( 29084231) Total cholesterol levels in large LDL ( 29084231) Total cholesterol levels in LDL ( 29084231) Total cholesterol levels in medium LDL ( 29084231) Total cholesterol levels in small LDL ( 29084231)	Glycemic traits (pregnancy) ( 23903356) Hemoglobin levels ( 32327693)
Interacting Genes		32 interacting genes: AGA AMBP APOE CRYAA CUBN F7 FCGRT FNDC3B FOXP1 HNF1A IMMT KLK3 LAMTOR5 LINC00624 LINC02582 LRP2 LUC7L2 NR5A2 ORM1 PFDN1 PON1 PRB3 RBP4 RNF181 RYR2 SRGN ST13 TK1 USP7 VWF WEE2-AS1 YWHAG	17 interacting genes: ALB BAG6 CCL3 CD44 CEP70 FHL3 GZMB NCALD PEX12 PF4 PSRC1 SGTA SGTB UBQLN1 UBQLN2 UBQLN4 UBR4
Entrez ID		213	5552
HPRD ID		00062	01513
Ensembl ID		ENSG00000163631	ENSG00000122862
Uniprot IDs		P02768	P10124
PDB IDs		1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1HK5 1N5U 1O9X 1TF0 1UOR 1YSX 2BX8 2BXA 2BXB 2BXC 2BXD 2BXE 2BXF 2BXG 2BXH 2BXI 2BXK 2BXL 2BXM 2BXN 2BXO 2BXP 2BXQ 2ESG 2I2Z 2I30 2N0X 2VDB 2VUE 2VUF 2XSI 2XVQ 2XVU 2XVV 2XVW 2XW0 2XW1 2YDF 3A73 3B9L 3B9M 3CX9 3JQZ 3JRY 3LU6 3LU7 3LU8 3SQJ 3TDL 3UIV 4BKE 4E99 4EMX 4G03 4G04 4HGK 4HGM 4IW1 4IW2 4K2C 4K71 4L8U 4L9K 4L9Q 4LA0 4LB2 4LB9 4N0F 4N0U 4S1Y 4Z69 5FUO 5GIX 5GIY 5ID7 5IFO 5IJF 5UJB 5VNW 5X52 5YB1 5YOQ 5Z0B 6A7P 6EZQ 6JE7 6L4K 6M4R 6M58 6M5D 6M5E 6QIO 6QIP 6R7S 6WUW 6XV0 6YG9 6ZL1 7A9C 7AAE 7AAI 7D6J 7DJN 7DL4 7EEK 7FFR 7FFS 7JWN 7QFE 7VR0 7VR9 7WKZ 7WLF 7WOJ 7WOK 7WZ9 7X7X 7Y2D 7Z57 8A9Q 8CKS 8EW4 8EW7 8EY5 8H0O 8ISM 8ITR 8ITT 8J8E 8K1Y 8OI2 8Q3F 8RCO 8RCP 8RGK 8RGL 8VAC 8VAE 8VAF 8Y9S 8Y9T 8Y9U 8YG7 8YXA 8YXB 8Z8V 9CSG
Enriched GO Terms of Interacting Partners?		Steroid Metabolic Process Protein-containing Complex Vascular Endothelial Growth Factor Binding Extracellular Space Blood Microparticle Negative Regulation Of Multicellular Organismal Process Vascular Endothelial Growth Factor Receptor Activity Genitalia Development Vitamin Transport Cobalamin Transport Vagina Development Alcohol Metabolic Process Regulation Of Biological Quality Regulation Of Multicellular Organismal Process Regulation Of TOR Signaling Response To Reactive Oxygen Species Platelet Alpha Granule Lumen TORC1 Signaling Negative Regulation Of Amyloid Fibril Formation Regulation Of Blood Coagulation Regulation Of Hemostasis Extracellular Region Regulation Of Defense Response To Bacterium Female Genitalia Development Vitamin Transmembrane Transport Regulation Of Amyloid Fibril Formation Negative Regulation Of Platelet Activation Transcytosis Receptor Complex Vascular Endothelial Growth Factor Signaling Pathway TOR Signaling U1 SnRNP Positive Regulation Of TOR Signaling Cytochrome C Metabolic Process Antioxidant Activity Extracellular Matrix Extracellular Exosome Negative Regulation Of Phospholipid Efflux Sterol Metabolic Process Chemical Homeostasis Negative Regulation Of Gene Expression High-density Lipoprotein Particle Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Cholesterol Metabolic Process Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Positive Regulation Of Multicellular Organismal Process Calcium Ion Homeostasis Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway	Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Proteolysis Involved In Protein Catabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRC Complex Protein Targeting Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Macromolecule Catabolic Process Protein Targeting To ER Response To Stress Proteasomal Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Proteasomal Protein Catabolic Process Proteolysis Regulation Of Cellular Response To Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Identical Protein Binding Establishment Of Protein Localization To Organelle Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Protein Targeting To Membrane Positive Regulation Of Protein Catabolic Process Cellular Response To Stress Autophagosome Response To Endoplasmic Reticulum Stress Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Catabolic Process Cytosol Autophagy Catabolic Process Monocyte Chemotaxis Organelle Organization Protein Insertion Into ER Membrane Regulation Of Autophagy Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Cytokine-mediated Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Molecular Adaptor Activity Regulation Of Macroautophagy Negative Regulation Of Store-operated Calcium Channel Activity Establishment Of Protein Localization Hsp70 Protein Binding
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