ERH and IGSF21

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ERH	IGSF21
Gene Name		enhancer of rudimentary homolog (Drosophila)	immunoglobin superfamily, member 21
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Midbody	Extracellular Region
	Molecular Function	Poly(A) RNA Binding
	Biological Process	Osteoblast Differentiation Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleoside Metabolic Process Cell Cycle
Pathways
Drugs
Diseases
GWAS			Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		19 interactors: APP CHTOP CIZ1 COPS6 CSNK2A1 CSNK2A2 CTDP1 FAM208B HSPA8 IGSF21 MED31 POLDIP3 RBM48 RPS6KA5 SETDB1 SH3GL2 TLE1 TP53 UNC119	32 interactors: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		2079	84966
HPRD ID		09026	11309
Ensembl ID			ENSG00000117154
Uniprot IDs		P84090	Q96ID5
PDB IDs		1W9G 2NML
Enriched GO Terms of Interacting Partners?		Axon Guidance Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Axonogenesis Positive Regulation Of Metabolic Process Axon Development Gene Expression Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Transcription, DNA-templated Regulation Of Gene Expression Cell Morphogenesis Involved In Differentiation RNA Biosynthetic Process RNA Metabolic Process Response To External Stimulus Regulation Of Chromosome Organization Neuron Projection Development Cell Projection Morphogenesis Regulation Of Mitotic Cell Cycle Phase Transition Cell Part Morphogenesis Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle Phase Transition Regulation Of RNA Metabolic Process Neuron Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Generation Of Neurons Cell Morphogenesis Neurogenesis Neuron Differentiation Mitotic Cell Cycle Process Cell Projection Organization Anatomical Structure Morphogenesis Positive Regulation Of Protein Metabolic Process Regulation Of Transcription, DNA-templated Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Locomotion Regulation Of Nucleic Acid-templated Transcription Notch Signaling Pathway Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Checkpoint Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process	Response To Wounding Regulation Of Apoptotic Process Regulation Of Cell Death Wound Healing Positive Regulation Of Protein Metabolic Process Response To Stress Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Negative Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Response To Stimulus Developmental Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Response To Xenobiotic Stimulus Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Catabolic Process Apoptotic Process Epidermal Growth Factor Receptor Signaling Pathway Nervous System Development ERBB Signaling Pathway Regulation Of Proteolysis Programmed Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Death Cellular Response To Stimulus Blood Coagulation Platelet Activation Hemostasis Regulation Of Protein Kinase Activity Response To Biotic Stimulus Multicellular Organismal Development Positive Regulation Of Catalytic Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Kinase Activity Positive Regulation Of Rac GTPase Activity Positive Regulation Of Endothelial Cell Migration Regulation Of Neuronal Synaptic Plasticity Regulation Of Kinase Activity Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Growth
Tagcloud ?		ambient avoid centre cereal decreasing equilibrium exceeding generates grain grains heating humidity infestation insect kept liable loading minimised moisture mould parts periphery shipboard shipment storage stow temperature temperatures threshold
Tagcloud (Difference) ?		ambient avoid centre cereal decreasing equilibrium exceeding generates grain grains heating humidity infestation insect kept liable loading minimised moisture mould parts periphery shipboard shipment storage stow temperature temperatures threshold
Tagcloud (Intersection) ?