ERBB4 and ADAM17

  • Number of citations of the paper that reports this interaction (PMID 15534001)
  • 76
  • Data Source:
  • HPRD (in vitro)

ERBB4

ADAM17

Gene Name erb-b2 receptor tyrosine kinase 4 ADAM metallopeptidase domain 17
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 39 interactors: ABL1 ABL2 ADAM17 ANKS1A ANKS1B BTC CD44 CRK CTGF DLG1 DLG2 DLG3 DLG4 EGFR ERBB2 ERBB3 EREG GRB2 HBEGF HDAC6 ITCH MUC1 NEDD4 NRG1 NRG2 NRG3 NRG4 PIK3R2 RASA1 RNF41 SHC1 SNTB2 STAT5A STAT5B SYK TAB2 TGFA TRO YAP1 14 interactors: DLG1 ERBB4 FHL2 MAD2L1 MAD2L2 NOTCH1 PTPN3 SH3D19 TGFA TIMP3 TNF TNFRSF1A TNFRSF1B TNFSF11
Entrez ID 2066 6868
HPRD ID 02767 04703
Ensembl ID ENSG00000178568 ENSG00000151694
Uniprot IDs Q15303 B2RNB2 P78536
PDB IDs 2AHX 2L2T 2LCX 2R4B 3BBT 3BBW 3BCE 3U2P 3U7U 3U9U 1BKC 1ZXC 2A8H 2DDF 2FV5 2FV9 2I47 2M2F 2OI0 3B92 3CKI 3E8R 3EDZ 3EWJ 3G42 3KMC 3KME 3L0T 3L0V 3LE9 3LEA 3LGP 3O64
Enriched GO Terms of Interacting Partners?
Tagcloud ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  her4  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally  transmembrane 
anchored  apma  arguing  betacellulin  bzatp  cd23  cd62  chimeras  constitutive  convertase  cytoplasmic  disintegrin  dispensable  domain  ectodomain  influences  influx  ionomycin  metalloprotease  metalloproteinase  motif  negatively  pro  retention  shedding  tgfalpha  translationally  transmembrane 
Tagcloud (Difference) ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  her4  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally 
anchored  apma  arguing  betacellulin  bzatp  cd23  cd62  chimeras  constitutive  convertase  cytoplasmic  disintegrin  dispensable  domain  ectodomain  influences  influx  ionomycin  metalloprotease  metalloproteinase  motif  negatively  pro  retention  shedding  tgfalpha  translationally 
Tagcloud (Intersection) ?
transmembrane