ERBB4 and PIK3R2

  • Number of citations of the paper that reports this interaction (PMID 16729043)
  • 123
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

ERBB4

PIK3R2

Gene Name erb-b2 receptor tyrosine kinase 4 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 39 interactors: ABL1 ABL2 ADAM17 ANKS1A ANKS1B BTC CD44 CRK CTGF DLG1 DLG2 DLG3 DLG4 EGFR ERBB2 ERBB3 EREG GRB2 HBEGF HDAC6 ITCH MUC1 NEDD4 NRG1 NRG2 NRG3 NRG4 PIK3R2 RASA1 RNF41 SHC1 SNTB2 STAT5A STAT5B SYK TAB2 TGFA TRO YAP1 51 interactors: APP ARRB1 AXL CBL CD28 CRKL CSF1 CSF1R DYDC1 EGF EGFR EPHA2 ERBB2 ERBB3 ERBB4 FBXL2 FGFR1 FYN GOLGA2 GRB2 GRN HCK IGF1R IKZF3 IRS1 IRS2 KIT KRAS KRT15 KRT20 KRT38 LAMB2 LTBP3 MRFAP1L1 PDGFRB PIK3CD RINT1 SEPT2 SHC1 SOCS1 SOCS6 SOCS7 SOS1 STAB1 SYK TEC TGFBR1 TGFBR2 TRIM23 WASF3 YWHAB
Entrez ID 2066 5296
HPRD ID 02767 04404
Ensembl ID ENSG00000178568 ENSG00000105647
Uniprot IDs Q15303 O00459
PDB IDs 2AHX 2L2T 2LCX 2R4B 3BBT 3BBW 3BCE 3U2P 3U7U 3U9U 2KT1 2XS6 3MTT 3O5Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  her4  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally  transmembrane 
acetylated  acetylations  chip  contrary  deacetylase  deacetylases  distally  dysregulated  encompassing  facilitates  featured  h2a  h3k9  hexokinase  hk2  irs2  l6  lysines  myotubes  p85beta  pharmacologically  responsive  reverted  template  treatable  trichostatin  tsa  tss  z 
Tagcloud (Difference) ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  her4  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally  transmembrane 
acetylated  acetylations  chip  contrary  deacetylase  deacetylases  distally  dysregulated  encompassing  facilitates  featured  h2a  h3k9  hexokinase  hk2  irs2  l6  lysines  myotubes  p85beta  pharmacologically  responsive  reverted  template  treatable  trichostatin  tsa  tss  z 
Tagcloud (Intersection) ?