ERBB4 and BTC

  • Number of citations of the paper that reports this interaction (PMID 11254912)
  • 5
  • Data Source:
  • HPRD (in vivo)

ERBB4

BTC

Gene Name erb-b2 receptor tyrosine kinase 4 betacellulin
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 39 interactors: ABL1 ABL2 ADAM17 ANKS1A ANKS1B BTC CD44 CRK CTGF DLG1 DLG2 DLG3 DLG4 EGFR ERBB2 ERBB3 EREG GRB2 HBEGF HDAC6 ITCH MUC1 NEDD4 NRG1 NRG2 NRG3 NRG4 PIK3R2 RASA1 RNF41 SHC1 SNTB2 STAT5A STAT5B SYK TAB2 TGFA TRO YAP1 6 interactors: EGFR ERBB2 ERBB4 GMPPA KRT31 MMP9
Entrez ID 2066 685
HPRD ID 02767 02643
Ensembl ID ENSG00000178568
Uniprot IDs Q15303 P35070
PDB IDs 2AHX 2L2T 2LCX 2R4B 3BBT 3BBW 3BCE 3U2P 3U7U 3U9U 1IOX 1IP0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  her4  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally  transmembrane 
1000mg  100mg  300mg  aes  already  arm  biliary  btcs  centers  endpoint  endpoints  favored  gemcitabine  infused  intravenously  italy  m2  monotherapy  multicenter  nct00753675  orr  pfs  placebo  plus  reporting  tolerability  v  vandetanib  worsening 
Tagcloud (Difference) ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  her4  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally  transmembrane 
1000mg  100mg  300mg  aes  already  arm  biliary  btcs  centers  endpoint  endpoints  favored  gemcitabine  infused  intravenously  italy  m2  monotherapy  multicenter  nct00753675  orr  pfs  placebo  plus  reporting  tolerability  v  vandetanib  worsening 
Tagcloud (Intersection) ?