ERBB4 and EREG

  • Number of citations of the paper that reports this interaction (PMID 9419975)
  • 11
  • Data Source:
  • HPRD (in vivo)

ERBB4

EREG

Gene Name erb-b2 receptor tyrosine kinase 4 epiregulin
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 39 interactors: ABL1 ABL2 ADAM17 ANKS1A ANKS1B BTC CD44 CRK CTGF DLG1 DLG2 DLG3 DLG4 EGFR ERBB2 ERBB3 EREG GRB2 HBEGF HDAC6 ITCH MUC1 NEDD4 NRG1 NRG2 NRG3 NRG4 PIK3R2 RASA1 RNF41 SHC1 SNTB2 STAT5A STAT5B SYK TAB2 TGFA TRO YAP1 2 interactors: EGFR ERBB4
Entrez ID 2066 2069
HPRD ID 02767 03638
Ensembl ID ENSG00000178568 ENSG00000124882
Uniprot IDs Q15303 O14944
PDB IDs 2AHX 2L2T 2LCX 2R4B 3BBT 3BBW 3BCE 3U2P 3U7U 3U9U 1K36 1K37
Enriched GO Terms of Interacting Partners?
Tagcloud ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  her4  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally  transmembrane 
amphiregulin  areg  betacellulin  btc  calgb  cd73  cetuximab  chemo  dusp4  epgn  epigen  epiregulin  erbb3  erbb4  folfiri  folfox  formalin  hbegf  her3  her4  implicate  kras  mcrc  modeled  multiplicative  nt5e  pfs  phlda1  tgfa 
Tagcloud (Difference) ?
180k  185k  45k  activates  encodes  erbb2  exists  fails  glycoprotein  heparin  heregulin  intrinsic  isoforms  ligand  mb453  mda  oncogene  p185erbb2  p45  presumed  proto  recombinant  ref  refs  shares  structurally  transmembrane 
amphiregulin  areg  betacellulin  btc  calgb  cd73  cetuximab  chemo  dusp4  epgn  epigen  epiregulin  erbb3  folfiri  folfox  formalin  hbegf  her3  implicate  kras  mcrc  modeled  multiplicative  nt5e  pfs  phlda1  tgfa 
Tagcloud (Intersection) ?
erbb4  her4