ATXN2L

Name	ataxin 2 like
Structure	No pdb structure
Interactors	42 interactors: ATXN1 BOLL CEBPA EPOR HADHA HOXA1 KRTAP12-4 MIR1-1 MIR10B MIR128-1 MIR128-2 MIR15B MIR16-2 MIR17 MIR19A MIR200C MIR205 MIR20B MIR21 MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR7-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MPL OGT
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding Cadherin Binding
	Biological Process	MRNA Metabolic Process Stress Granule Assembly
GWAS	Albumin-globulin ratio ( 29403010 ) Allergic disease (asthma, hay fever or eczema) ( 29679657 ) Body fat distribution (arm fat ratio) ( 30664634 ) Body fat distribution (leg fat ratio) ( 30664634 ) Body fat distribution (trunk fat ratio) ( 30664634 ) Body fat percentage ( 26833246 ) Body mass index ( 20935630 28448500 28552196 ) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500 ) Body mass index in physically active individuals ( 28448500 ) Brain morphology (MOSTest) ( 32665545 ) Cognitive ability ( 29186694 ) Cognitive ability (MTAG) ( 29186694 ) Crohn's disease ( 28067908 ) Educational attainment ( 23722424 25201988 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Extremely high intelligence ( 29520040 ) Hand grip strength ( 29691431 ) Inflammatory bowel disease ( 28067908 ) Intelligence ( 28530673 ) Intelligence (MTAG) ( 29326435 ) Lamb consumption ( 32066663 ) Left-handedness ( 32989287 ) Pediatric autoimmune diseases ( 26301688 ) Waist circumference ( 28552196 ) Weight ( 28552196 )
Entrez ID	11273
HPRD ID	06394
Ensembl ID	ENSG00000168488
Uniprot IDs	H3BUF6 Q8WWM7
PDB IDs	Not available
GO Terms Enriched among Interactors ?	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Negative Regulation Of Cell Migration Regulation Of Translation Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Regulation Of Macromolecule Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Extracellular Space Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Regulation Of Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Proliferation Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Connective Tissue Replacement Negative Regulation Of Signal Transduction