ATXN2L and HADHA

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ATXN2L	HADHA
Gene Name		ataxin 2-like	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Stress Granule Membrane Nuclear Speck	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Mitochondrial Nucleoid
	Molecular Function	Protein Binding Poly(A) RNA Binding	Fatty-acyl-CoA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Acetyl-CoA C-acetyltransferase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity Protein Complex Binding NAD Binding
	Biological Process	Regulation Of Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly	Fatty Acid Beta-oxidation Phospholipid Metabolic Process Response To Insulin Cardiolipin Acyl-chain Remodeling Response To Drug Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways			Acyl chain remodeling of CL Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Mitochondrial Fatty Acid Beta-Oxidation Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Glycerophospholipid biosynthesis Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of myristoyl-CoA to lauroyl-CoA Phospholipid metabolism
Drugs			NADH
Diseases
GWAS		Body mass index ( 20935630) Educational attainment ( 23722424)
Protein-Protein Interactions		4 interactors: ATXN1 EPOR HADHA MPL	6 interactors: ABCF2 ATXN2L CD74 NR4A1 PIN1 YWHAQ
Entrez ID		11273	3030
HPRD ID		06394	02934
Ensembl ID		ENSG00000168488	ENSG00000084754
Uniprot IDs		H3BUF6 Q8WWM7	B4DRH6 E9KL44 P40939
PDB IDs
Enriched GO Terms of Interacting Partners?		Erythropoietin-mediated Signaling Pathway Cellular Response To Erythropoietin Cardiolipin Acyl-chain Remodeling Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
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