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EPHB3 and AFDN
Number of citations of the paper that reports this interaction (PubMedID
9707552
)
36
Data Source:
BioGRID
(pull down)
HPRD
(in vitro, two hybrid, in vivo)
EPHB3
AFDN
Description
EPH receptor B3
afadin, adherens junction formation factor
Image
GO Annotations
Cellular Component
Extracellular Region
Cytosol
Plasma Membrane
Membrane
Dendrite
Cell Projection
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Cell-cell Junction
Adherens Junction
Nuclear Speck
Cell Junction
Cell-cell Contact Zone
Pore Complex
Tight Junction
Anchoring Junction
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Tyrosine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Ephrin Receptor Activity
Transmembrane-ephrin Receptor Activity
Protein Binding
ATP Binding
Axon Guidance Receptor Activity
Kinase Activity
Transferase Activity
Protein Binding
Small GTPase Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Actin Filament Binding
Biological Process
Angiogenesis
Urogenital System Development
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Nervous System Development
Axon Guidance
Axonal Fasciculation
Cell Migration
Central Nervous System Projection Neuron Axonogenesis
Corpus Callosum Development
Regulation Of Cell-cell Adhesion
Retinal Ganglion Cell Axon Guidance
Cell-substrate Adhesion
Substrate Adhesion-dependent Cell Spreading
Regulation Of GTPase Activity
Protein Autophosphorylation
Ephrin Receptor Signaling Pathway
Thymus Development
Digestive Tract Morphogenesis
Regulation Of Axonogenesis
Positive Regulation Of Synapse Assembly
Roof Of Mouth Development
Dendritic Spine Development
Dendritic Spine Morphogenesis
Cell Adhesion
Signal Transduction
Cell-cell Signaling
Positive Regulation Of Gene Expression
Positive Regulation Of Cell-cell Adhesion
Cell Differentiation
Negative Regulation Of Cell Migration
Regulation Of Protein Localization
Cell Junction Organization
Cell-cell Adhesion Mediated By Cadherin
Pore Complex Assembly
Establishment Of Protein Localization To Plasma Membrane
Bicellular Tight Junction Assembly
Establishment Of Endothelial Intestinal Barrier
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways
EPH-Ephrin signaling
EPH-Ephrin signaling
EPHB-mediated forward signaling
EPHB-mediated forward signaling
Ephrin signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells
Drugs
(5R)-2-sulfanyl-5-[4-(trifluoromethyl)benzyl]-1,3-thiazol-4(5H)-one
Diseases
GWAS
Facial morphology traits (63 three-dimensional facial segments) (
29459680
)
Nicotine dependence symptom count (
25555482
)
Nose size (
27182965
)
White matter hyperintensity volume x hypertension interaction (2df) (
33293549
)
Number of alcoholic drinks required to feel an effect (long-term average) (
31270906
)
Interacting Genes
14 interacting genes:
AFDN
CRK
EFNB3
ERBB2
FBXO7
FYN
GBE1
HPCAL1
HSF2BP
LNX1
NFRKB
RASA1
RNF186
RYK
39 interacting genes:
BCR
CTNNA1
DSCAM
EPHA7
EPHB2
EPHB3
EPHB6
F11R
HRAS
JAG1
LMO2
MRAS
NECTIN1
NECTIN2
NECTIN3
NECTIN4
NRXN1
NRXN2
NRXN3
PFN1
PICK1
RALGDS
RAP1A
RAP1GAP
RAP2A
RIN1
RIT1
RIT2
RNF10
RRAS
RRAS2
SMAD2
SORBS1
SORBS2
SSX2IP
TJP1
USP9X
YWHAB
YWHAG
Entrez ID
2049
4301
HPRD ID
03502
01164
Ensembl ID
ENSG00000182580
ENSG00000130396
Uniprot IDs
P54753
A0A1P7ZIN0
A0A804HJ20
A8MQ02
G1UI22
J3KN01
P55196
PDB IDs
3P1I
3ZFY
5L6O
5L6P
1T2M
1XZ9
2AIN
2EXG
5A6C
7QCR
Enriched GO Terms of Interacting Partners
?
Ephrin Receptor Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Ephrin Receptor Binding
Enzyme-linked Receptor Protein Signaling Pathway
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Cellular Component Organization
Neuron Projection Development
Regulation Of Cell Adhesion
Regulation Of Neuron Projection Development
Neuron Projection Guidance
Axon Guidance
Positive Regulation Of Cell Adhesion
Regulation Of Anatomical Structure Morphogenesis
Reelin-mediated Signaling Pathway
Regulation Of Neuron Apoptotic Process
Negative Regulation Of Cell Development
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Projection Organization
Protein Tyrosine Kinase Activity
Regulation Of Cell Shape
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Developmental Process
Signaling Receptor Binding
Regulation Of Protein Targeting To Membrane
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Cell Projection Organization
Phosphotyrosine Residue Binding
Negative Regulation Of Immune System Process
Cellular Developmental Process
Plasma Membrane Bounded Cell Projection Organization
Negative Regulation Of Developmental Process
T Cell Costimulation
Regulation Of Multicellular Organismal Development
Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission
Negative Regulation Of Axonogenesis
Hippocampal Mossy Fiber To CA3 Synapse
Regulation Of Lymphocyte Activation
Regulation Of Cell-cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Activity
Negative Regulation Of Programmed Cell Death
Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Apoptotic Process
Cell Junction Organization
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Cellular Response To Glycine
Response To Singlet Oxygen
1,4-alpha-glucan Branching Enzyme Activity
Glial Cytoplasmic Inclusion
Classical Lewy Body
Lewy Body Corona
Signal Transduction
GDP Binding
Regulation Of Cell Junction Assembly
Plasma Membrane
Small GTPase-mediated Signal Transduction
Cell Adhesion
Ras Protein Signal Transduction
Cell-cell Adhesion
Cell Adhesion Molecule Binding
Membrane
Regulation Of Synapse Assembly
Adherens Junction
G Protein Activity
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Anchoring Junction
Ephrin Receptor Activity
Regulation Of Cell Projection Organization
Transmembrane-ephrin Receptor Activity
Neuron Projection Guidance
Axon Guidance
Protein Localization To Cell Junction
GTPase Activity
Plasma Membrane Bounded Cell Projection Organization
Cell Junction Organization
Neuroligin Family Protein Binding
Synapse
Regulation Of Cellular Component Organization
Cell Junction Assembly
Modulation Of Chemical Synaptic Transmission
Regulation Of Cell Communication
Regulation Of Signaling
Postsynaptic Membrane Assembly
Intracellular Signaling Cassette
Regulation Of Synapse Organization
Focal Adhesion
Negative Regulation Of Cellular Component Organization
Apical Junction Complex
Regulation Of Locomotion
Zonula Adherens
Presynaptic Membrane
Cell Projection Organization
Postsynaptic Membrane Organization
Dendrite
Regulation Of Cell Projection Assembly
Neuron Projection Development
GTP Binding
Axon Guidance Receptor Activity
Cell Adhesion Mediator Activity
Regulation Of Cell Motility
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
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Tagcloud (Difference)
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Tagcloud (Intersection)
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