EPHB3 and GBE1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		EPHB3	GBE1
Description		EPH receptor B3	1,4-alpha-glucan branching enzyme 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Membrane Dendrite Cell Projection	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Axon Guidance Receptor Activity Kinase Activity Transferase Activity	Catalytic Activity 1,4-alpha-glucan Branching Enzyme Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein Binding Transferase Activity Glycosyltransferase Activity Carbohydrate Binding Cation Binding
	Biological Process	Angiogenesis Urogenital System Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Axon Guidance Axonal Fasciculation Cell Migration Central Nervous System Projection Neuron Axonogenesis Corpus Callosum Development Regulation Of Cell-cell Adhesion Retinal Ganglion Cell Axon Guidance Cell-substrate Adhesion Substrate Adhesion-dependent Cell Spreading Regulation Of GTPase Activity Protein Autophosphorylation Ephrin Receptor Signaling Pathway Thymus Development Digestive Tract Morphogenesis Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Roof Of Mouth Development Dendritic Spine Development Dendritic Spine Morphogenesis	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Generation Of Precursor Metabolites And Energy Negative Regulation Of Neuron Apoptotic Process
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	Glycogen synthesis Glycogen storage disease type IV (GBE1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Nicotine dependence symptom count ( 25555482) Nose size ( 27182965) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)	Adult body size ( 32376654) Body mass index ( 25673413) Cadmium levels ( 26025379) Chronotype ( 30696823) Daytime nap ( 33568662) Extraversion ( 27918536) Femur bone mineral density x serum urate levels interaction ( 34046847) Hand grip strength ( 29691431) Intraocular pressure ( 31798171) Intraocular pressure and central corneal thickness (multi-trait analysis) ( 31798171) Lead levels in blood ( 25820613) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Meat-related diet ( 32066663) Photic sneeze reflex ( 30899065) Processed meat consumption ( 32066663) Risk-taking tendency (4-domain principal component model) ( 30643258) Waist circumference ( 25673412)
Interacting Genes		14 interacting genes: AFDN CRK EFNB3 ERBB2 FBXO7 FYN GBE1 HPCAL1 HSF2BP LNX1 NFRKB RASA1 RNF186 RYK	8 interacting genes: CEBPA EPHB3 KLHL20 PGD PRMT6 RIPK3 TRDMT1 UBC
Entrez ID		2049	2632
HPRD ID		03502	01985
Ensembl ID		ENSG00000182580	ENSG00000114480
Uniprot IDs		P54753	Q04446 Q59ET0
PDB IDs		3P1I 3ZFY 5L6O 5L6P	4BZY 5CLT 5CLW
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Binding Enzyme-linked Receptor Protein Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Regulation Of Cellular Component Organization Neuron Projection Development Regulation Of Cell Adhesion Regulation Of Neuron Projection Development Neuron Projection Guidance Axon Guidance Positive Regulation Of Cell Adhesion Regulation Of Anatomical Structure Morphogenesis Reelin-mediated Signaling Pathway Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Development Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Protein Tyrosine Kinase Activity Regulation Of Cell Shape Positive Regulation Of Protein Targeting To Membrane Regulation Of Developmental Process Signaling Receptor Binding Regulation Of Protein Targeting To Membrane Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Projection Organization Phosphotyrosine Residue Binding Negative Regulation Of Immune System Process Cellular Developmental Process Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Developmental Process T Cell Costimulation Regulation Of Multicellular Organismal Development Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission Negative Regulation Of Axonogenesis Hippocampal Mossy Fiber To CA3 Synapse Regulation Of Lymphocyte Activation Regulation Of Cell-cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Activity Negative Regulation Of Programmed Cell Death Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Cell Junction Organization Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Response To Glycine Response To Singlet Oxygen 1,4-alpha-glucan Branching Enzyme Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona	Gland Development RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Hematopoietic Or Lymphoid Organ Development Thymus Development Pentose Biosynthetic Process D-gluconate Metabolic Process Phosphogluconate Dehydrogenase (decarboxylating) Activity Cortical Microtubule Plus-end Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Protein K33-linked Ubiquitination Type II Interferon Binding Histone H3R2 Methyltransferase Activity Histone H2AR3 Methyltransferase Activity CHOP-C/EBP Complex TRNA (cytidine-5-)-methyltransferase Activity Execution Phase Of Necroptosis Histone Arginine N-methyltransferase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?