ARHGAP17 and SH3GLB1

Number of citations of the paper that reports this interaction (PMID 11431473)
23

Data Source:
HPRD (in vitro)

		ARHGAP17	SH3GLB1
Gene Name		Rho GTPase activating protein 17	SH3-domain GRB2-like endophilin B1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Tight Junction	Golgi Membrane Cytoplasm Mitochondrial Outer Membrane Extracellular Vesicular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Apoptotic Process Positive Regulation Of Protein Oligomerization Protein Oligomerization
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10	22 interactors: ADAM15 ADAM9 AMPH APP ARHGAP17 BAX BIN1 CMTM5 DNM1 DNM2 FUNDC1 GADD45A GADD45G HTT MTA1 PSMA1 SH3GLB2 SH3KBP1 SYNJ1 TFIP11 TPD52L2 ZNF576
Entrez ID		55114	51100
HPRD ID		12207	15333
Ensembl ID		ENSG00000140750	ENSG00000097033
Uniprot IDs		Q68EM7	Q9Y371
PDB IDs
Enriched GO Terms of Interacting Partners?		Endocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Vesicle-mediated Transport Immune Response-regulating Cell Surface Receptor Signaling Pathway Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway T Cell Costimulation Innate Immune Response Platelet Activation Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Response To Wounding Phagocytosis Positive Regulation Of Cell Activation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Immune Response Immune Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Defense Response Regulation Of Cell-cell Adhesion Neuron Projection Morphogenesis Regulation Of Lymphocyte Activation Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Cell-cell Adhesion Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Activation Neuron Projection Development Cell Migration Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of T Cell Activation Cell Projection Morphogenesis Locomotion Transport Regulation Of Signaling	Endocytosis Learning Regulation Of Cell Cycle Regulation Of Catalytic Activity Apoptotic Process Programmed Cell Death Vesicle-mediated Transport Neuron Apoptotic Process Cell Death Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Neuron Death Positive Regulation Of Catalytic Activity Establishment Of Vesicle Localization Positive Regulation Of Cellular Protein Metabolic Process Vesicle Localization Signaling Response To Radiation Single-organism Behavior Cell Communication Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Learning Or Memory Regulation Of P38MAPK Cascade Cognition Regulation Of Signaling Regulation Of Cellular Process Positive Regulation Of Proteolysis Synaptic Vesicle Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Behavior Positive Regulation Of Cell Death Regulation Of Apoptotic Process Establishment Of Organelle Localization Response To Light Stimulus Regulation Of Cell Death Response To Abiotic Stimulus Response To Ionizing Radiation Response To Stress Regulation Of Protein Binding Regulation Of Signal Transduction Positive Regulation Of Transport Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Membrane Permeability Organelle Localization Endoplasmic Reticulum Calcium Ion Homeostasis Synaptic Vesicle Endocytosis Signal Transduction
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