ARHGAP17 and SH3GLB1

Number of citations of the paper that reports this interaction (PubMedID 11431473)
0

Data Source:
HPRD (in vitro)

		ARHGAP17	SH3GLB1
Description		Rho GTPase activating protein 17	SH3 domain containing GRB2 like, endophilin B1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Membrane Anchoring Junction	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Golgi Apparatus Cytosol Membrane Nuclear Body Midbody Cytoplasmic Vesicle Protein-containing Complex
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding	Fatty Acid Binding Protein Binding Lipid Binding Lysophosphatidic Acid Acyltransferase Activity Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Phosphatidylinositol 3-kinase Activator Activity
	Biological Process	Signal Transduction Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction	Phosphatidic Acid Biosynthetic Process Autophagy Apoptotic Process Phospholipid Biosynthetic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein-containing Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death 'de Novo' Post-translational Protein Folding Membrane Organization Membrane Fission Positive Regulation Of Membrane Tubulation Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		16 interacting genes: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10	52 interacting genes: ABHD5 ADAM15 ADAM9 AGTRAP AMPH APP ARFIP2 ARHGAP17 BAX BIN1 C1D CACFD1 CDKN2D CMTM5 COQ8A DESI2 DNM2 EXOSC5 F8A1 FAM114A2 FN1 FUNDC1 GADD45A GADD45G GSTP1 HTATIP2 HTT IRGM ITGB1BP2 MAL2 MTA1 PSMA1 RABAC1 RABGGTB RHEX RIC8A SH3GLB2 SH3KBP1 SIN3A SMIM5 SNX1 SNX4 SYNGR3 SYNJ1 SYP TAX1BP1 TFIP11 TPD52 TPD52L2 TTN UBL7 ZNF576
Entrez ID		55114	51100
HPRD ID		12207	15333
Ensembl ID		ENSG00000140750	ENSG00000097033
Uniprot IDs		Q68EM7	A0A087WW40 A0A140VJU5 A0A994J549 Q9Y371
PDB IDs			6UP6 6UPN 9G2R 9G2U 9G2W
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Binding Endocytosis Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Component Organization Actin Cytoskeleton Organization Phosphotyrosine Residue Binding Import Into Cell Actin Filament-based Process Regulation Of Protein-containing Complex Assembly Regulation Of Cell Projection Organization Regulation Of Endocytosis Positive Regulation Of Supramolecular Fiber Organization Cytosol Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein-containing Complex Assembly Cell-cell Junction Positive Regulation Of Locomotion Regulation Of Actin Filament-based Process Positive Regulation Of Lamellipodium Organization Regulation Of Supramolecular Fiber Organization Regulation Of Cell-substrate Adhesion Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of MAPK Cascade SH2 Domain Binding Cytoskeleton Organization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Non-membrane Spanning Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Substrate Adhesion-dependent Cell Spreading Regulation Of Actin Filament Organization Phospholipase Activator Activity Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Lamellipodium Organization B Cell Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Positive Regulation Of Organelle Organization Positive Regulation Of Intracellular Signal Transduction Fc Receptor Signaling Pathway Regulation Of Cell Adhesion Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Regulation Of Substrate Adhesion-dependent Cell Spreading Signal Transduction Regulation Of Organelle Organization Regulation Of Vesicle-mediated Transport Positive Regulation Of Cell Migration Leukocyte Activation Positive Regulation Of Cell Motility	Cytoplasmic Vesicle Protein Binding SH3 Domain Binding Synaptic Vesicle Vesicle-mediated Transport Insulin Receptor Binding Leptin Receptor Binding Endocytosis Integrin Binding BH3 Domain Binding Cytoplasm Synaptic Vesicle Transport Synaptic Vesicle Endocytosis Presynaptic Endocytosis Positive Regulation Of Programmed Cell Death Peptidase Activator Activity Positive Regulation Of Catabolic Process Establishment Of Vesicle Localization
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