CRTC2 and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CRTC2	CCDC57
Description		CREB regulated transcription coactivator 2	coiled-coil domain containing 57
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Extracellular Exosome	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Spindle Microtubule Centriolar Satellite
	Molecular Function	Transcription Coactivator Activity Protein Binding CAMP Response Element Binding Protein Binding	Protein Binding
	Biological Process	Gluconeogenesis Positive Regulation Of CREB Transcription Factor Activity Glucose Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Protein Homotetramerization Cellular Response To CAMP	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways		Transcriptional activation of mitochondrial biogenesis Heme signaling Expression of BMAL (ARNTL), CLOCK, and NPAS2
Drugs
Diseases
GWAS		Age at first birth ( 27798627 34211149) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		15 interacting genes: ATPAF2 CCDC57 CDC23 CREB1 MFHAS1 NEDD4 PPP3CA PRKAA1 SIK1 SIK2 SIK3 SUFU YWHAB YWHAG YWHAZ	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 CATSPERT CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SAXO4 SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPMIP2 SPMIP6 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		200186	284001
HPRD ID		12347	14150
Ensembl ID		ENSG00000160741	ENSG00000176155
Uniprot IDs		Q53ET0	A0A590UJT6 Q2TAC2
PDB IDs		4HTM
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Localization To Nucleus Phosphoserine Residue Binding Protein Modification Process Regulation Of Protein Localization To Nucleus Intracellular Signal Transduction Negative Regulation Of Protein Localization Regulation Of TORC1 Signaling Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of TOR Signaling Protein Sequestering Activity Phosphorylation Regulation Of Cell Communication Signal Transduction Regulation Of Signaling Negative Regulation Of Cell Communication Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Signaling Cellular Response To Glucose Starvation Protein Localization To Lysosome Protein Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Protein Targeting Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell TORC1 Signaling Negative Regulation Of Biosynthetic Process Protein Domain Specific Binding Regulation Of Signal Transduction Proteasomal Protein Catabolic Process Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell TOR Signaling Positive Regulation Of TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Immune Response To Tumor Cell Protein Localization To Vacuole Phosphate-containing Compound Metabolic Process Regulation Of Protein Localization Negative Regulation Of Macromolecule Metabolic Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Regulation Of T Cell Mediated Immune Response To Tumor Cell Modification-dependent Protein Catabolic Process Negative Regulation Of Protein Import Into Nucleus Positive Regulation Of Immune Response To Tumor Cell Protein Catabolic Process Negative Regulation Of Metabolic Process Response To Light Stimulus Regulation Of Nucleocytoplasmic Transport	Protein Binding Spliceosomal Complex Nucleus Cytoskeleton MRNA Splicing, Via Spliceosome RNA Splicing Axonemal A Tubule Inner Sheath RNA Splicing, Via Transesterification Reactions
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?