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CRTC2
Description
CREB regulated transcription coactivator 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Extracellular Exosome
Molecular Function
Transcription Coactivator Activity
Protein Binding
CAMP Response Element Binding Protein Binding
Biological Process
Gluconeogenesis
Positive Regulation Of CREB Transcription Factor Activity
Glucose Homeostasis
Positive Regulation Of Transcription By RNA Polymerase II
Protein Homotetramerization
Cellular Response To CAMP
Pathways
Transcriptional activation of mitochondrial biogenesis
Heme signaling
Expression of BMAL (ARNTL), CLOCK, and NPAS2
Drugs
Diseases
GWAS
Age at first birth (
27798627
34211149
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cooked vegetable consumption (
32066663
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (min-P) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Empathy quotient (
29527006
)
Fish- and plant-related diet (
32066663
)
Fruit consumption (
32066663
)
Raw vegetable consumption (
32066663
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
15 interacting genes:
ATPAF2
CCDC57
CDC23
CREB1
MFHAS1
NEDD4
PPP3CA
PRKAA1
SIK1
SIK2
SIK3
SUFU
YWHAB
YWHAG
YWHAZ
Entrez ID
200186
HPRD ID
12347
Ensembl ID
ENSG00000160741
Uniprot IDs
Q53ET0
PDB IDs
4HTM
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Protein Localization To Nucleus
Phosphoserine Residue Binding
Protein Modification Process
Regulation Of Protein Localization To Nucleus
Intracellular Signal Transduction
Negative Regulation Of Protein Localization
Regulation Of TORC1 Signaling
Protein Phosphorylation
Negative Regulation Of Signal Transduction
Regulation Of TOR Signaling
Protein Sequestering Activity
Phosphorylation
Regulation Of Cell Communication
Signal Transduction
Regulation Of Signaling
Negative Regulation Of Cell Communication
Proteolysis Involved In Protein Catabolic Process
Negative Regulation Of Signaling
Cellular Response To Glucose Starvation
Protein Localization To Lysosome
Protein Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Protein Targeting
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell
TORC1 Signaling
Negative Regulation Of Biosynthetic Process
Protein Domain Specific Binding
Regulation Of Signal Transduction
Proteasomal Protein Catabolic Process
Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell
TOR Signaling
Positive Regulation Of TOR Signaling
Negative Regulation Of TOR Signaling
Negative Regulation Of Immune Response To Tumor Cell
Protein Localization To Vacuole
Phosphate-containing Compound Metabolic Process
Regulation Of Protein Localization
Negative Regulation Of Macromolecule Metabolic Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Regulation Of T Cell Mediated Immune Response To Tumor Cell
Modification-dependent Protein Catabolic Process
Negative Regulation Of Protein Import Into Nucleus
Positive Regulation Of Immune Response To Tumor Cell
Protein Catabolic Process
Negative Regulation Of Metabolic Process
Response To Light Stimulus
Regulation Of Nucleocytoplasmic Transport
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