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THAP8 and DYNLL1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
THAP8
DYNLL1
Gene Name
THAP domain containing 8
dynein, light chain, LC8-type 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Kinetochore
Nucleus
Cytoplasm
Mitochondrion
Centrosome
Cytosol
Cytoplasmic Dynein Complex
Microtubule
Plasma Membrane
COP9 Signalosome
Membrane
Extracellular Vesicular Exosome
Primary Cilium
Mitotic Spindle
Ciliary Tip
Molecular Function
DNA Binding
Metal Ion Binding
Motor Activity
Protein Binding
Protein C-terminus Binding
Enzyme Binding
Protein Domain Specific Binding
Nitric-oxide Synthase Regulator Activity
Protein Homodimerization Activity
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Transport
Apoptotic Process
Organelle Organization
Microtubule-based Process
Female Gamete Generation
Anatomical Structure Morphogenesis
Viral Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Substantia Nigra Development
Actin Cytoskeleton Organization
Negative Regulation Of Phosphorylation
Regulation Of Catalytic Activity
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
Organelle biogenesis and maintenance
Activation of BH3-only proteins
Assembly of the primary cilium
G2/M Transition
Anchoring of the basal body to the plasma membrane
Regulation of PLK1 Activity at G2/M Transition
Cell Cycle, Mitotic
Intraflagellar transport
Loss of proteins required for interphase microtubule organization from the centrosome
Activation of BIM and translocation to mitochondria
Loss of Nlp from mitotic centrosomes
MHC class II antigen presentation
Programmed Cell Death
Centrosome maturation
Mitotic G2-G2/M phases
Recruitment of mitotic centrosome proteins and complexes
Adaptive Immune System
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
DYNLL1
SETDB1
TFIP11
TMED9
TP53
77 interactors:
ACTB
ACTC1
ACTG1
ALDOA
AMBRA1
AMOTL2
B3GALT4
BCAS1
BCL2L11
BMF
C14orf1
CA2
CACNB1
CCDC36
CLIP2
CS
DAZ1
DLG4
DLGAP1
DNAJB9
DNM2
DNM3
DNMT1
DYNC1H1
DYNC1I1
EEF1A1
GAPDH
GLUD1
GLUL
GNB2L1
GPHN
GRIN3A
HIP1R
HSPA8
INPP1
IQUB
KANK2
LDHA
MAP1B
MARK3
MAST2
ME2
MTA1
MTR
MYO10
MYO5A
NDUFA4L2
NFKBIA
NOS1
NRF1
NTRK1
NTRK2
NTRK3
PAK1
PAN2
PARD3
PAX6
PFKM
PFKP
PKIA
PKIB
PKIG
POLH
RAB4A
RGS2
SHROOM3
TERT
THAP8
TNFRSF14
TP53BP1
TUBA3C
TUBB
TXNDC17
VIM
ZHX1
ZMYND11
ZNF354A
Entrez ID
199745
8655
HPRD ID
15501
03334
Ensembl ID
ENSG00000161277
ENSG00000088986
Uniprot IDs
B4DKM9
Q8NA92
P63167
Q6FGH9
PDB IDs
1CMI
3ZKE
3ZKF
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Organelle Organization
Positive Regulation Of Mitochondrion Organization
Regulation Of Mitochondrion Organization
Spliceosomal Complex Disassembly
Negative Regulation Of Macromitophagy
Oligodendrocyte Apoptotic Process
Regulation Of Organelle Organization
Negative Regulation Of Helicase Activity
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Intracellular Transport
Organ Development
Positive Regulation Of Cell Aging
Positive Regulation Of Thymocyte Apoptotic Process
Mitochondrial DNA Repair
Organelle Organization
RNA Metabolic Process
Regulation Of Mitochondrion Degradation
T Cell Proliferation Involved In Immune Response
B Cell Lineage Commitment
Glial Cell Apoptotic Process
Oxidative Stress-induced Premature Senescence
Histone H3-K9 Trimethylation
Gene Expression
Apoptotic Signaling Pathway
ER Overload Response
Negative Regulation Of Macroautophagy
Stress-induced Premature Senescence
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Positive Regulation Of T Cell Apoptotic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
DNA Strand Renaturation
DNA Damage Response, Signal Transduction Resulting In Transcription
Mitotic Cell Cycle Arrest
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Golgi Vesicle Budding
Regulation Of Intracellular Transport
Regulation Of Thymocyte Apoptotic Process
Replicative Senescence
Positive Regulation Of Mitochondrial Membrane Permeability
Determination Of Adult Lifespan
Positive Regulation Of Lymphocyte Apoptotic Process
Circadian Behavior
Mitochondrial DNA Metabolic Process
Positive Regulation Of Histone Deacetylation
Rhythmic Behavior
Nervous System Development
Movement Of Cell Or Subcellular Component
Cell Differentiation
Developmental Process
Regulation Of Cellular Component Organization
Response To Organic Substance
Regulation Of Cellular Localization
Neuron Projection Morphogenesis
Axonogenesis
Cellular Response To Stimulus
Synapse Organization
Neuron Projection Development
Neuron Development
Regulation Of Cellular Protein Metabolic Process
Response To Stimulus
Neuron Differentiation
Regulation Of Protein Metabolic Process
Axon Development
Cell Projection Morphogenesis
Response To External Stimulus
Anatomical Structure Morphogenesis
Cell Projection Organization
Cell Morphogenesis Involved In Neuron Differentiation
Cell Part Morphogenesis
Cellular Process
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Positive Regulation Of Protein Homooligomerization
Cell Morphogenesis
Axon Guidance
Negative Regulation Of Phosphorylation
Regulation Of Cellular Process
Glycolytic Process
Locomotion
Cell Development
Negative Regulation Of Protein Phosphorylation
Cytoskeleton Organization
Regulation Of Phosphorus Metabolic Process
Regulation Of Phosphorylation
Membrane Organization
Regulation Of CAMP-dependent Protein Kinase Activity
Cell Morphogenesis Involved In Differentiation
Anatomical Structure Development
Generation Of Neurons
System Development
Response To Stress
Regulation Of Protein Phosphorylation
Multicellular Organismal Development
Neuromuscular Junction Development
Pyruvate Metabolic Process
Actin Filament-based Process
Tagcloud
?
1inq53a
250viqd
52gqvd
adapter
attempt
capsid
defective
dynein
hiv
immunodeficiency
integrase
interaction
kd
ma
motifs
mutational
p150glued
particulate
predicts
proper
q252a
replication
requirement
reverse
steps
tctex
transcriptase
uncoating
Tagcloud (Difference)
?
1inq53a
250viqd
52gqvd
adapter
attempt
capsid
defective
dynein
hiv
immunodeficiency
integrase
interaction
kd
ma
motifs
mutational
p150glued
particulate
predicts
proper
q252a
replication
requirement
reverse
steps
tctex
transcriptase
uncoating
Tagcloud (Intersection)
?