HNRNPH3 and PIM2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HNRNPH3	PIM2
Description		heterogeneous nuclear ribonucleoprotein H3	Pim-2 proto-oncogene, serine/threonine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribonucleoprotein Complex	Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing Epithelial Cell Differentiation Regulation Of RNA Splicing	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Apoptotic Mitochondrial Changes Response To Virus Positive Regulation Of Autophagy Macroautophagy Positive Regulation Of Macroautophagy Negative Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of DNA-templated Transcription Protein Stabilization
Pathways
Drugs		Copper
Diseases
GWAS
Interacting Genes		100 interacting genes: ADORA2A ANXA11 CCL13 CHERP CRMP1 DDX17 DDX5 EEF1G ERG ERG28 HNRNPA0 HNRNPA1 HNRNPD HNRNPF HNRNPH1 HNRNPU HNRNPUL1 IL7R KAT5 MAPK6 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NCBP3 PIM2 RBM4 RPS4X SLC22A2 TTR UTP14A ZMYM2	16 interacting genes: ATXN1 BAD CUTC DAPK1 FBH1 FBP1 FBXO7 GSK3B HNRNPH3 HSF1 IKBKG NDUFB8 RPL21 SOCS1 TRIM14 ZNF821
Entrez ID		3189	11040
HPRD ID		03818	02244
Ensembl ID		ENSG00000096746	ENSG00000102096
Uniprot IDs		B4DHY1 P31942 Q53F48	Q9P1W9
PDB IDs			2IWI 4X7Q
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of MRNA Stability Regulation Of Translation Negative Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Vasculature Development Regulation Of RNA Stability Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Motility Regulation Of Metabolic Process Regulation Of Angiogenesis Negative Regulation Of Locomotion Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Migration Extracellular Space Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus	Positive Regulation Of Autophagy Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Catabolic Process Regulation Of Type B Pancreatic Cell Development Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Autophagy Protein Kinase Binding Regulation Of Cellular Response To Stress Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Cell Development Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Cellular Response To Heat Positive Regulation Of Programmed Cell Death Extrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Cellular Response To Stress Positive Regulation Of Apoptotic Signaling Pathway Nucleus Regulation Of Macromolecule Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Hemopoiesis Positive Regulation Of Proteolysis Positive Regulation Of Cell Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Positive Regulation Of Leukocyte Differentiation Positive Regulation Of Cell Differentiation Cellular Response To Lipid DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Regulation Of Microtubule Anchoring At Centrosome Cellular Response To Nitroglycerin Negative Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of Primary Metabolic Process Regulation Of Lymphocyte Differentiation Negative Regulation Of Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
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