AGXT and PEX5

Number of citations of the paper that reports this interaction (PMID 20178365)
7

Data Source:
BioGRID (unspecified method)
HPRD (in vivo)

		AGXT	PEX5
Gene Name		alanine-glyoxylate aminotransferase	peroxisomal biogenesis factor 5
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix Peroxisome Peroxisomal Matrix	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Serine-pyruvate Transaminase Activity Receptor Binding Protein Binding Alanine-glyoxylate Transaminase Activity Transaminase Activity Amino Acid Binding Pyridoxal Phosphate Binding Protein Homodimerization Activity	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-cysteine Catabolic Process Cellular Nitrogen Compound Metabolic Process L-alanine Catabolic Process Pyruvate Biosynthetic Process Small Molecule Metabolic Process Glyoxylate Metabolic Process Oxalic Acid Secretion Response To Glucocorticoid Response To CAMP	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways		Glyoxylate metabolism Metabolism of amino acids and derivatives
Drugs		Pyridoxal Phosphate L-Serine Glycine L-Alanine (Aminooxy)Acetic Acid N\'-Pyridoxyl-Lysine-5\'-Monophosphate 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		3 interactors: ACAT1 PEX5 SNCAIP	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		189	5830
HPRD ID		05048	02684
Ensembl ID		ENSG00000172482	ENSG00000139197
Uniprot IDs		P21549	B4DR50 B4E0T2 P50542
PDB IDs		1H0C 1J04 3R9A 4I8A	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Cholesterol Storage Lipid Modification Carboxylic Acid Catabolic Process Metanephric Proximal Convoluted Tubule Development Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Macrophage Derived Foam Cell Differentiation Metanephric Proximal Tubule Development Cholesterol Esterification Protein Import Into Peroxisome Matrix, Docking Ketone Body Catabolic Process Proximal Tubule Development Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Protein Oligomerization Regulation Of Amyloid Precursor Protein Biosynthetic Process Very-low-density Lipoprotein Particle Assembly Peroxisomal Membrane Transport Negative Regulation Of Protein Oligomerization Ketone Body Biosynthetic Process Cellular Ketone Body Metabolic Process Protein Import Into Peroxisome Matrix Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Metanephric Nephron Tubule Development Protein-lipid Complex Assembly Regulation Of Inclusion Body Assembly Branched-chain Amino Acid Catabolic Process Brain Development Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Head Development Very Long-chain Fatty Acid Metabolic Process Cerebral Cortex Neuron Differentiation Dopamine Metabolic Process Cholesterol Efflux Regulation Of Protein Oligomerization Regulation Of Glycoprotein Biosynthetic Process Metanephric Epithelium Development Adipose Tissue Development Cellular Lipid Metabolic Process Central Nervous System Development Lipid Storage Endoplasmic Reticulum Organization Catecholamine Metabolic Process Fatty Acid Beta-oxidation Peroxisome Organization Carboxylic Acid Metabolic Process	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?		aim2 alox12 built cpg discriminate discriminated e85 epigenome false il10 jak3 lcn2 leukocyte manifested methqtl obtainable p1075 p180 p220 p348 p624 p817 p86 pac penalized resectable smoker statistic zap70	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		aim2 alox12 built cpg discriminate discriminated e85 epigenome false il10 jak3 lcn2 leukocyte manifested methqtl obtainable p1075 p180 p220 p348 p624 p817 p86 pac penalized resectable smoker statistic zap70	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?