AGXT and MORN5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AGXT	MORN5
Description		alanine--glyoxylate aminotransferase	MORN repeat containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Matrix Cytosol	Cilium Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	L-serine-pyruvate Transaminase Activity Protein Binding Alanine-glyoxylate Transaminase Activity Transaminase Activity Amino Acid Binding Transferase Activity Pyridoxal Phosphate Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	L-serine Metabolic Process Notch Signaling Pathway Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-cysteine Catabolic Process L-alanine Catabolic Process Glyoxylate Metabolic Process Oxalic Acid Secretion
Pathways		Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs		Pyridoxal phosphate Serine Glycine Alanine Aminooxyacetic acid N(6)-(pyridoxal phosphate)-L-lysine 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Diseases		Primary hyperoxaluria (HP)
GWAS		Height ( 25282103 31562340) Urinary metabolites ( 26352407)	Malaria ( 31844061)
Interacting Genes		39 interacting genes: ACAT1 ACTMAP ATXN1L BATF3 CFAP68 CHIC2 CYSRT1 EFS FAM168B FHL5 FNTB FOSB GLP1R HOXA1 KRT31 KRT34 KRT37 KRT40 KRTAP1-1 KRTAP12-3 KRTAP3-1 KRTAP6-3 KRTAP8-1 KRTAP9-2 LPXN MDFI MORN5 NBPF19 NOTCH2NLA OIP5 PEX5 PLA2G10 PRDM6 PRICKLE4 RFX6 SNCAIP SPRYD7 TRAPPC14 TTC19	9 interacting genes: AGXT ENKD1 GAS2L2 HAT1 MISP POM121 STAMBPL1 TLX3 USP2
Entrez ID		189	254956
HPRD ID		05048	12947
Ensembl ID		ENSG00000172482	ENSG00000185681
Uniprot IDs		P21549	A0A0A0MTF6 Q5VZ52
PDB IDs		1H0C 1J04 2YOB 3R9A 4CBR 4CBS 4I8A 4KXK 4KYO 5F9S 5HHY 5LUC 5OFY 5OG0 6RV0 6RV1 7NS7
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Negative Regulation Of B Cell Receptor Signaling Pathway	Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Orientation L-serine-pyruvate Transaminase Activity Establishment Of Spindle Localization Spindle Localization Glycine Biosynthetic Process, By Transamination Of Glyoxylate Glyoxylate Catabolic Process Alanine-glyoxylate Transaminase Activity Oxalic Acid Secretion Protein Deubiquitination Protein Modification By Small Protein Removal Microtubule Cytoskeleton Organization Actin Filament Mitotic Spindle Astral Microtubule End Protein Localization To Microtubule Plus-end Glycine Biosynthetic Process L-alanine Catabolic Process L-alanine Metabolic Process L-cysteine Catabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?