SPTSSA and GET1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPTSSA	GET1
Description		serine palmitoyltransferase small subunit A	guided entry of tail-anchored proteins factor 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Serine Palmitoyltransferase Complex	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex
	Molecular Function	Serine C-palmitoyltransferase Activity Protein Binding	Protein Binding Protein-membrane Adaptor Activity
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Intracellular Protein Localization Sphingolipid Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Sensory Perception Of Sound Protein Insertion Into ER Membrane Synapse Organization Protein Stabilization Establishment Of Localization In Cell Otic Vesicle Development Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane
Pathways		Sphingolipid de novo biosynthesis	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Intraocular pressure ( 29785010 31959993)
Interacting Genes		8 interacting genes: CYSRT1 GET1 GLP1R HERPUD2 RHBDL1 TMEM31 TUBB3 VKORC1	28 interacting genes: ABHD5 APOA2 APOL2 AQP1 CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 HMOX2 HTATIP2 ORMDL3 PLPP4 PTPN9 RASGRP3 RTP2 SERP2 SLC35E3 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42
Entrez ID		171546	7485
HPRD ID		16610	04224
Ensembl ID		ENSG00000165389	ENSG00000182093
Uniprot IDs		Q969W0	O00258
PDB IDs		6M4N 6M4O 7CQI 7CQK 7K0I 7K0J 7K0K 7K0L 7K0M 7K0N 7K0O 7K0P 7K0Q 7YIU 7YIY 7YJ1 7YJ2	6SO5 8CQZ 8CR1 8CR2
Enriched GO Terms of Interacting Partners?			Basolateral Plasma Membrane Membrane Serine Palmitoyltransferase Complex
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