SPTSSA and HERPUD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

		SPTSSA	HERPUD2
Description		serine palmitoyltransferase small subunit A	HERPUD family member 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Serine Palmitoyltransferase Complex	Membrane
	Molecular Function	Serine C-palmitoyltransferase Activity Protein Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Intracellular Protein Localization Sphingolipid Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process	Response To Unfolded Protein Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Intraocular pressure ( 29785010 31959993)	Cognitive function ( 24684796) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Essential hypertension (time to event) ( 32589924) Obesity-related traits ( 23251661) PR interval ( 30046033 30679814 32439900)
Interacting Genes		8 interacting genes: CYSRT1 GET1 GLP1R HERPUD2 RHBDL1 TMEM31 TUBB3 VKORC1	17 interacting genes: ALG10 CYB561A3 EFNA5 IER3IP1 MS4A13 NAF1 RBM11 SLC35A4 SLC39A9 SLC7A1 SPTSSA TAS2R10 TMBIM6 TMEM144 TMEM31 TMEM60 UBE2B
Entrez ID		171546	64224
HPRD ID		16610	07984
Ensembl ID		ENSG00000165389	ENSG00000122557
Uniprot IDs		Q969W0	Q9BSE4
PDB IDs		6M4N 6M4O 7CQI 7CQK 7K0I 7K0J 7K0K 7K0L 7K0M 7K0N 7K0O 7K0P 7K0Q 7YIU 7YIY 7YJ1 7YJ2	2KDB
Enriched GO Terms of Interacting Partners?			Membrane
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