FAM9A and PRMT1

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		FAM9A	PRMT1
Gene Name		family with sequence similarity 9, member A	protein arginine methyltransferase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Methyltransferase Activity N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Identical Protein Binding Histone Methyltransferase Activity (H4-R3 Specific) Poly(A) RNA Binding
	Biological Process		Chromatin Organization Regulation Of Transcription, DNA-templated Protein Methylation Cell Surface Receptor Signaling Pathway Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Neuron Projection Development Histone H4-R3 Methylation Negative Regulation Of Megakaryocyte Differentiation
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: JMJD6 KDM1A PRMT1 SETD8 ZDHHC17	93 interactors: AR ARPC3 ASH2L AXIN1 BRCA1 BTG1 BTG2 C17orf53 C20orf196 C4orf17 CAPRIN1 CDC37 CEP162 CIRBP CNOT8 COIL DAXX DCAF16 DCAF8 DHX9 EIF4A1 ESR1 EWSR1 FAM83D FAM9A FBL FGF2 FLII FUS GPATCH2L GRHL3 GRIP1 HABP4 HIST1H3A HIST1H4A HIST2H4A HIST4H4 HNF4A HNRNPA1 HNRNPK HNRNPR HNRNPU HNRNPUL1 IDH3B IFNAR1 IGSF21 ILF3 KHDRBS1 KHDRBS2 KHDRBS3 LRIF1 MBP MECOM MED31 MLST8 NCOA1 NCOA2 NCOA3 NOL4 NRIP1 OFCC1 PIAS1 PPARA PRMT8 QKI RELA RNF187 RUNX1 S100A8 SAMD3 SPAG8 SPEG SPSB1 SPSB2 STAT1 STAT5A SUPT5H SYNCRIP TAF15 TBX6 TERF2 THRB TP53 VHL VPS72 WDFY3 WDR33 WDYHV1 YLPM1 YWHAG ZBTB14 ZMYM5 ZNF451
Entrez ID		171482	3276
HPRD ID		06506	04257
Ensembl ID		ENSG00000183304	ENSG00000126457
Uniprot IDs		Q8IZU1	B4DJ87 H7C2I1 Q99873
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone Modification Chromatin Modification Chromatin Organization Regulation Of Megakaryocyte Differentiation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hematopoietic Progenitor Cell Differentiation Chromosome Organization Histone Demethylation Protein Demethylation Regulation Of Signal Transduction By P53 Class Mediator Cellular Protein Modification Process Demethylation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Regulation Of Primitive Erythrocyte Differentiation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Cellular Protein Metabolic Process Histone Methylation Regulation Of Response To DNA Damage Stimulus Protein Methylation Regulation Of Myeloid Cell Differentiation Peptidyl-amino Acid Modification Protein Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Myeloid Cell Differentiation Peptidyl-lysine Modification Peptidyl-lysine Monomethylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Organelle Organization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Recognition Of Apoptotic Cell Histone H3-K4 Demethylation Leukocyte Differentiation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Megakaryocyte Differentiation Cellular Macromolecule Biosynthetic Process Positive Regulation Of Hormone Biosynthetic Process Macromolecule Biosynthetic Process Peptidyl-arginine N-methylation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Histone H4-R3 Methylation Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Phagocytosis, Recognition Regulation Of Intracellular Signal Transduction Histone Arginine Methylation	Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process MRNA Processing Chromatin Organization Cellular Process Chromatin Modification Response To Hormone MRNA Metabolic Process RNA Processing Chromosome Organization Cellular Response To Hormone Stimulus Metabolic Process Response To Organic Substance
Tagcloud ?		aberrantly aberration ap1s2 brcc3 cpxcr1 cxorf45 ddx53 dmd fhl1 gabre gjb1 hdac8 hypermethylated hypomethylated hypomethylation hysterectomy irreversible leiomyoma leiomyomas myometrium nxf5 paired pcdh11x ream taf1 tag uterine vbp1 xist	bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Difference) ?		aberrantly aberration ap1s2 brcc3 cpxcr1 cxorf45 ddx53 dmd fhl1 gabre gjb1 hdac8 hypermethylated hypomethylated hypomethylation hysterectomy irreversible leiomyoma leiomyomas myometrium nxf5 paired pcdh11x ream taf1 tag uterine vbp1 xist	bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Intersection) ?