FAM9A and LCE1E

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM9A	LCE1E
Description		family with sequence similarity 9 member A	late cornified envelope 1E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleolus
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Epidermis Development Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Creatinine levels ( 29403010) Estradiol levels ( 34255042) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965)	Asthma ( 31619474) Inflammatory skin disease ( 25574825)
Interacting Genes		38 interacting genes: ARPC3 CTNNA3 ESRRA ESRRG FAM9B H2BC15 HOMER1 INTS12 KDM1A KMT5A LCE1E MCRS1 NAB2 NXF1 PHC1 PICK1 PRMT1 PRR20A PRR20B PRR20C PRR20D PRR20E RNF151 RNF4 RUNX1T1 SDCBP STAC3 THAP1 TRAF2 TRAF5 TRIM41 TRIM54 TXLNA VCX ZBTB6 ZDHHC17 ZFP91 ZNF775	67 interacting genes: ALPP CATSPER1 CYSRT1 EFEMP2 FAM9A FUCA2 GRN KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2B LCE2C LCE2D LCE3B LCE4A LCE5A MACO1 MEOX2 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 PIAS2 RGS17 RGS20 RNF4 SMCP SPRY1 TGM1 TRIM42 ZCCHC7
Entrez ID		171482	353135
HPRD ID		06506	13969
Ensembl ID		ENSG00000183304	ENSG00000186226
Uniprot IDs		Q8IZU1	Q5T753
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Zinc Ion Binding Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H4 Methyltransferase Activity Regulation Of RNA Metabolic Process Ubiquitin Protein Ligase Activity Negative Regulation Of RNA Metabolic Process Thioesterase Binding CD40 Signaling Pathway Interleukin-17-mediated Signaling Pathway Estrogen Response Element Binding CD40 Receptor Complex Regulation Of Nucleobase-containing Compound Metabolic Process Protein K63-linked Ubiquitination Signaling Adaptor Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Metal Ion Binding	Intermediate Filament Keratin Filament Keratinization Epidermis Development Hair Cycle Tissue Development Cytosol Protein Binding Identical Protein Binding
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