DFFA and CIDEB

Number of citations of the paper that reports this interaction (PMID 10619428)
22

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		DFFA	CIDEB
Gene Name		DNA fragmentation factor, 45kDa, alpha polypeptide	cell death-inducing DFFA-like effector b
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Lipid Particle Cytosol	Lipid Particle Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Apoptotic DNA Fragmentation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Process Thymocyte Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Apoptotic DNA Fragmentation	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity
Pathways		Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CASP3 CASP7 CIDEB DFFB EWSR1 GZMB GZMM NECAB2 STRN4 YWHAG YWHAZ	3 interactors: CIDEA DFFA DFFB
Entrez ID		1676	27141
HPRD ID		03531	11981
Ensembl ID			ENSG00000136305
Uniprot IDs		O00273	Q9UHD4
PDB IDs		1IBX 1IYR 1KOY	1D4B
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Process Regulation Of Mitochondrion Organization Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Protein Processing Activation Of Cysteine-type Endopeptidase Activity Regulation Of Apoptotic Process Zymogen Activation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Regulation Of Cell Death Positive Regulation Of Organelle Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Apoptotic DNA Fragmentation Positive Regulation Of Peptidase Activity Intracellular Signal Transduction Cytolysis Apoptotic Nuclear Changes Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Intracellular Transport Positive Regulation Of Proteolysis Regulation Of Organelle Organization Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Regulation Of Cellular Component Organization DNA Catabolic Process, Endonucleolytic Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Intracellular Transport Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Signal Transduction Negative Regulation Of Protein Serine/threonine Kinase Activity DNA Catabolic Process Golgi Reassembly Apoptotic Chromosome Condensation Granzyme-mediated Apoptotic Signaling Pathway Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization	Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Execution Phase Of Apoptosis Apoptotic DNA Fragmentation Regulation Of Execution Phase Of Apoptosis Apoptotic Nuclear Changes Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis DNA Catabolic Process, Endonucleolytic Apoptotic Process Programmed Cell Death Cell Death Death DNA Catabolic Process Negative Regulation Of Apoptotic DNA Fragmentation Nucleic Acid Phosphodiester Bond Hydrolysis Apoptotic Chromosome Condensation Positive Regulation Of Sequestering Of Triglyceride Thymocyte Apoptotic Process Aromatic Compound Catabolic Process Response To Stilbenoid T Cell Apoptotic Process Negative Regulation Of Lipid Catabolic Process Temperature Homeostasis Cellular Macromolecule Catabolic Process Positive Regulation Of Lipid Storage Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cytokine Secretion Negative Regulation Of Cell Death Negative Regulation Of Tumor Necrosis Factor Production Lipid Storage Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production DNA Metabolic Process Chromosome Condensation Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Lipid Metabolic Process Regulation Of Apoptotic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Cell Death Negative Regulation Of DNA Metabolic Process Negative Regulation Of Protein Secretion Nitrogen Compound Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?		cd40 cd71 dysplastic effector erythroid erythropoiesis etv6 fas glya gm hematopoiesis hemoglobin ineffective leukemic making megakaryocyte meps microrna mir9 mirna mirnas profiling progenitors robust runx1 sorted speculating sub ut	87mg ags alteration arrayed bad bcl2 bcl2l11 bfar bnip3l casp7 cidea combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tnfrsf10b tnfrsf11b tnfrsf1a tnfrsf21 tp73 traf3 uncovering
Tagcloud (Difference) ?		cd40 cd71 dysplastic effector erythroid erythropoiesis etv6 fas glya gm hematopoiesis hemoglobin ineffective leukemic making megakaryocyte meps microrna mir9 mirna mirnas profiling progenitors robust runx1 sorted speculating sub ut	87mg ags alteration arrayed bad bcl2 bcl2l11 bfar bnip3l casp7 cidea combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tnfrsf10b tnfrsf11b tnfrsf1a tnfrsf21 tp73 traf3 uncovering
Tagcloud (Intersection) ?