ZBTB8A and ACOT12

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ZBTB8A	ACOT12
Description		zinc finger and BTB domain containing 8A	acyl-CoA thioesterase 12
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Cytosol Intercellular Bridge
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Acetyl-CoA Hydrolase Activity Protein Binding ATP Binding Lipid Binding Hydrolase Activity Thiolester Hydrolase Activity Identical Protein Binding Carboxylic Ester Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Acetyl-CoA Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		76 interacting genes: ACOT12 AEN AP1M1 AP2M1 ARMC7 ARMCX1 BAZ2B BLK BYSL CBX8 CCDC33 CDC37 CDKL3 CEP70 CSNK1D CWF19L2 DDX6 DVL2 DVL3 EHHADH EIF1AD EP300 FAM161A FAM90A1 FXR2 GPATCH2L HIC2 JRK KAT5 KAT7 KIF5B KIF9 KIFC3 LGALS14 LMO3 LNX1 MCM10 MFAP1 MRPL11 MYO15B NTAQ1 PAXIP1 PIAS2 PRKAA2 PRPF3 PRR34 PSMC1 RAD23A RPL9 SDCBP SYT6 TCEA2 TNIP3 TRIM41 UBE2I YES1 ZBTB17 ZBTB24 ZBTB48 ZBTB49 ZCCHC10 ZGPAT ZMAT2 ZNF138 ZNF250 ZNF276 ZNF329 ZNF35 ZNF408 ZNF417 ZNF438 ZNF497 ZNF572 ZNF587 ZNF648 ZNF837	9 interacting genes: ACOT7 MEOX1 MEOX2 NAA10 NAA11 PAX5 PAX6 REL ZBTB8A
Entrez ID		653121	134526
HPRD ID		18902	16680
Ensembl ID		ENSG00000160062	ENSG00000172497
Uniprot IDs		D3DPQ1 Q96BR9	Q8WYK0
PDB IDs			3B7K 4MOB 4MOC
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Histone H4 Acetyltransferase Activity Peptidyl-lysine Acetylation Regulation Of Macromolecule Metabolic Process Peptide Lactyltransferase (CoA-dependent) Activity Histone Acetyltransferase Complex Nucleoplasm Histone Acetyltransferase Activity Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly Protein Acetylation Organelle Disassembly Regulation Of Metabolic Process Positive Regulation Of Neuron Projection Arborization Frizzled Binding Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Histone H4K16 Acetyltransferase Activity Identical Protein Binding Internal Protein Amino Acid Acetylation Phosphatidylethanolamine Biosynthetic Process Regulation Of Protein Deacetylation Kinesin Complex Signal Transduction By P53 Class Mediator	Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein N-terminal-serine Acetyltransferase Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Somite Specification RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity HMG Box Domain Binding N-terminal Protein Amino Acid Acetylation Segment Specification Somite Development Sequence-specific DNA Binding Chromatin Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Embryonic Pattern Specification Regulation Of Transcription By RNA Polymerase II Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Long-chain Fatty-acyl-CoA Catabolic Process Palmitic Acid Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cerebral Cortex Development Pattern Specification Process Positive Regulation Of RNA Metabolic Process Sclerotome Development Habenula Development Pallium Development Medium-chain Fatty Acid Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Embryonic Organ Morphogenesis Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification NF-kappaB Complex Long-chain Fatty Acyl-CoA Binding Medium-chain Fatty-acyl-CoA Metabolic Process Nucleus Forebrain Dorsal/ventral Pattern Formation Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?