ZBTB8A and ZBTB49

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB8A	ZBTB49
Description		zinc finger and BTB domain containing 8A	zinc finger and BTB domain containing 49
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Cytoskeleton
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS			Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
Interacting Genes		76 interacting genes: ACOT12 AEN AP1M1 AP2M1 ARMC7 ARMCX1 BAZ2B BLK BYSL CBX8 CCDC33 CDC37 CDKL3 CEP70 CSNK1D CWF19L2 DDX6 DVL2 DVL3 EHHADH EIF1AD EP300 FAM161A FAM90A1 FXR2 GPATCH2L HIC2 JRK KAT5 KAT7 KIF5B KIF9 KIFC3 LGALS14 LMO3 LNX1 MCM10 MFAP1 MRPL11 MYO15B NTAQ1 PAXIP1 PIAS2 PRKAA2 PRPF3 PRR34 PSMC1 RAD23A RPL9 SDCBP SYT6 TCEA2 TNIP3 TRIM41 UBE2I YES1 ZBTB17 ZBTB24 ZBTB48 ZBTB49 ZCCHC10 ZGPAT ZMAT2 ZNF138 ZNF250 ZNF276 ZNF329 ZNF35 ZNF408 ZNF417 ZNF438 ZNF497 ZNF572 ZNF587 ZNF648 ZNF837	12 interacting genes: CEP70 CIB1 EP300 GOPC PICK1 POT1 TP53 TRAF2 TRAF3 VAC14 ZBTB2 ZBTB8A
Entrez ID		653121	166793
HPRD ID		18902	10335
Ensembl ID		ENSG00000160062	ENSG00000168826
Uniprot IDs		D3DPQ1 Q96BR9	Q6ZSB9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Histone H4 Acetyltransferase Activity Peptidyl-lysine Acetylation Regulation Of Macromolecule Metabolic Process Peptide Lactyltransferase (CoA-dependent) Activity Histone Acetyltransferase Complex Nucleoplasm Histone Acetyltransferase Activity Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly Protein Acetylation Organelle Disassembly Regulation Of Metabolic Process Positive Regulation Of Neuron Projection Arborization Frizzled Binding Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Histone H4K16 Acetyltransferase Activity Identical Protein Binding Internal Protein Amino Acid Acetylation Phosphatidylethanolamine Biosynthetic Process Regulation Of Protein Deacetylation Kinesin Complex Signal Transduction By P53 Class Mediator	Regulation Of DNA-binding Transcription Factor Activity Transcription Coactivator Binding Identical Protein Binding Tumor Necrosis Factor-mediated Signaling Pathway Thioesterase Binding CD40 Receptor Complex Regulation Of Cellular Component Organization TORC2 Signaling Positive Regulation Of DNA-binding Transcription Factor Activity Apoptotic Signaling Pathway Regulation Of Organelle Organization Negative Regulation Of Cellular Component Organization Programmed Necrotic Cell Death Negative Regulation Of Telomere Maintenance Via Telomerase Platelet Formation Cytokine-mediated Signaling Pathway Apoptotic Process T Cell Lineage Commitment Intrinsic Apoptotic Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Tumor Necrosis Factor Receptor Binding Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Programmed Cell Death Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cell Death RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Telomere Maintenance Positive Regulation Of Gene Expression, Epigenetic Regulation Of Phosphorus Metabolic Process Somitogenesis Peptidyl-lysine Propionylation Segmentation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Transcription Initiation-coupled Chromatin Remodeling Histone Butyryltransferase Activity Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Nutrient Levels Histone Crotonyltransferase Activity Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Cellular Response To Glucose Starvation Regulation Of Telomere Maintenance Via Telomere Lengthening TORC2 Complex Disassembly
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